Which has the lower trailing P/E, MEDP or PEN?

MEDP has the lower trailing P/E: MEDP trades at 34.74 and PEN at 79.31. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, MEDP or PEN?

Over the past five years, MEDP grew revenue faster — MEDP at a 22.03% CAGR versus PEN at 17.52%.

Is MEDP or PEN more profitable?

MEDP runs the higher net margin — MEDP at 17.67% versus PEN at 10.67%.

How have MEDP and PEN total returns compared?

Over the past 10 years, MEDP delivered 34.47% and PEN delivered 16.41% annualized total return. Past performance doesn't predict future results.

Medpace Holdings, Inc. (MEDP) vs Penumbra, Inc. (PEN)

A side-by-side comparison of Medpace Holdings, Inc. and Penumbra, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 3, 2026. Differences are shown without an overall score or investment verdict.

MEDP

Medpace Holdings, Inc.

$16.52B

$591.99HealthcareDelayed quote: Sep 3, 2026, 3:55 PM EDT

PEN

Penumbra, Inc.

$12.66B

$321.33HealthcareDelayed quote: Sep 3, 2026, 3:55 PM EDT

Total return — MEDP vs PEN

growth of $100 · dividends reinvested · last 10y

MEDP +1927.8% (+35.1%/yr)PEN +353.2% (+16.3%/yr)MEDP compounded faster over this window

MEDP PEN

MEDP vs PEN: by the numbers

•MEDP is the larger company ($16.52B vs $12.66B market cap).
•MEDP trades at the lower trailing earnings multiple (34.74 vs 79.31 P/E), one valuation lens rather than an overall verdict.
•MEDP converts more revenue to profit (17.67% vs 10.67% net margin).
•MEDP grew revenue faster over the past five years (22.03% vs 17.52% CAGR).

Metrics side by side

Valuation

Metric	MEDP	PEN
P/E ratio	34.74	79.31
Forward P/E	33.69	68.56
P/S ratio	6.13	8.49
P/B ratio	39.31	8.34
EV / EBITDA	27.28	62.51
FCF yield	4.30%	1.69%

Profitability

Metric	MEDP	PEN
Gross margin	28.76%	67.84%
Operating margin	20.97%	12.45%
Net margin	17.67%	10.67%
ROE	113.29%	10.49%
ROIC	77.00%	8.48%

Growth (annualized)

Metric	MEDP	PEN
Revenue CAGR (5Y)	22.03%	17.52%
EPS CAGR (5Y)	30.90%	21.94%
FCF CAGR (5Y)	23.40%	83.74%
Total return CAGR (5Y)	25.06%	3.06%

Frequently asked

Which has the lower trailing P/E, MEDP or PEN?: MEDP has the lower trailing P/E: MEDP trades at 34.74 and PEN at 79.31. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, MEDP or PEN?: Over the past five years, MEDP grew revenue faster — MEDP at a 22.03% CAGR versus PEN at 17.52%.
Is MEDP or PEN more profitable?: MEDP runs the higher net margin — MEDP at 17.67% versus PEN at 10.67%.
How have MEDP and PEN total returns compared?: Over the past 10 years, MEDP delivered 34.47% and PEN delivered 16.41% annualized total return. Past performance doesn't predict future results.

Go deeper

Full MEDP analysis Full PEN analysis Interactive comparison tool

Dig into the metrics

Medpace P/E ratio Penumbra P/E ratio Medpace ROE Penumbra ROE Medpace operating margin Penumbra operating margin Medpace revenue growth Penumbra revenue growth Medpace free cash flow Penumbra free cash flow

Medpace & Penumbra appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 3, 2026.