23andMe Holding Co. (ME) vs DENTSPLY SIRONA Inc. (XRAY)
XRAY leads on 6 of 9 compared metrics.
A side-by-side comparison of 23andMe Holding Co. and DENTSPLY SIRONA Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
Total return — ME vs XRAY
growth of $100 · last 5yME -99.7%XRAY -72.2%XRAY compounded faster
Log scale — wide-divergence pair
ME XRAY
ME vs XRAY: by the numbers
- •XRAY is the larger company ($2.02B vs $15M market cap).
- •Both run net losses; XRAY's is the smaller (-17.06% vs -134.54% net margin).
- •XRAY grew revenue faster over the past five years (1.12% vs -9.07% CAGR).
- •XRAY pays a dividend (4.76% yield) while ME does not currently pay one.
Which is better, ME or XRAY?
Metric tally: ME 3 · XRAY 6It depends on what you're optimizing for:
GrowthXRAY(faster 5Y revenue CAGR)
QualityXRAY(higher ROIC)
Valuation
| Metric | ME | XRAY |
|---|---|---|
| Forward P/E | — | 7.11 |
| P/S ratio | 0.10● | 0.55 |
| P/B ratio | 0.51● | 1.53 |
| FCF yield | — | 5.16% |
Profitability
| Metric | ME | XRAY |
|---|---|---|
| Gross margin | 53.33%● | 48.93% |
| Operating margin | -114.00% | 5.87%● |
| Net margin | -134.54% | -17.06%● |
| ROE | -721.75% | -47.65%● |
| ROIC | -553.10% | 5.67%● |
Dividends
| Metric | ME | XRAY |
|---|---|---|
| Dividend yield | — | 4.76% |
Growth (annualized)
| Metric | ME | XRAY |
|---|---|---|
| Revenue CAGR (5Y) | -9.07% | 1.12%● |
| EPS CAGR (5Y) | — | -0.93% |
| FCF CAGR (5Y) | — | -29.96% |
| Total return CAGR (5Y) | -68.93% | -29.72%● |
Frequently asked
- Which is better, ME or XRAY?
- It depends on your goal. growth: XRAY (faster 5Y revenue CAGR); quality: XRAY (higher ROIC). Across all compared metrics, XRAY leads 6 to 3.
- Which has grown faster, ME or XRAY?
- Over the past five years, XRAY grew revenue faster — ME at a -9.07% CAGR versus XRAY at 1.12%.
- Does ME or XRAY pay a bigger dividend?
- XRAY pays a dividend (4.76% yield) while ME does not currently pay one.
- Which has been the better investment, ME or XRAY?
- Over the past 5-year, XRAY delivered the higher annualized total return — ME at -68.93% versus XRAY at -15.61%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
23andMe P/E ratioDENTSPLY SIRONA P/E ratio23andMe dividend yieldDENTSPLY SIRONA dividend yield23andMe ROEDENTSPLY SIRONA ROE23andMe operating marginDENTSPLY SIRONA operating margin23andMe revenue growthDENTSPLY SIRONA revenue growth23andMe free cash flowDENTSPLY SIRONA free cash flow
23andMe & DENTSPLY SIRONA appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.