23andMe Holding Co. (ME) vs TransMedics Group, Inc. (TMDX)

A side-by-side comparison of 23andMe Holding Co. and TransMedics Group, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 4, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnME vs TMDX

growth of $100 · dividends reinvested · last 5y
ME -99.7%TMDX +666.0%TMDX compounded faster
Log scale — wide-divergence pair
01101001k10kStart $100202120222023202420252026$0$766
ME TMDX

ME vs TMDX: by the numbers

  • TMDX is the larger company ($2.81B vs $15M market cap).
  • TMDX is profitable (27.04% net margin) while ME runs a net loss (-134.54%).
  • TMDX grew revenue faster over the past five years (90.79% vs -9.07% CAGR).

Metrics side by side

Valuation

MetricMETMDX
P/E ratioN/A18.66
Forward P/EN/A44.58
P/S ratio0.104.64
P/B ratio0.515.97
PEG ratioN/A0.05
EV / EBITDAN/A26.33
FCF yieldN/A5.13%

Profitability

MetricMETMDX
Gross margin53.33%59.09%
Operating margin-126.72%14.85%
Net margin-134.54%27.04%
ROE-721.75%34.80%
ROIC-553.10%10.94%

Growth (annualized)

MetricMETMDX
Revenue CAGR (5Y)-9.07%90.79%
Total return CAGR (5Y)-68.93%23.91%

Frequently asked

Which has grown faster, ME or TMDX?
Over the past five years, TMDX grew revenue faster — ME at a -9.07% CAGR versus TMDX at 90.79%.
Is ME or TMDX more profitable?
TMDX runs the higher net margin — ME at -134.54% versus TMDX at 27.04%.
How have ME and TMDX total returns compared?
Over the past 5 years, ME delivered -68.93% and TMDX delivered 23.91% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 4, 2026.