23andMe Holding Co. (ME) vs Tempus AI, Inc. (TEM)
A side-by-side comparison of 23andMe Holding Co. and Tempus AI, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 30, 2026. Differences are shown without an overall score or investment verdict.
ME
23andMe Holding Co.
$0.61HealthcareAt close: Mar 19, 2026, 4:00 PM ET
TEM
Tempus AI, Inc.
$41.90HealthcareDelayed quote: Jul 30, 2026, 9:30 AM EDT
Total return — ME vs TEM
growth of $100 · dividends reinvested · last 2yME -92.4%TEM +21.1%TEM compounded faster
Log scale — wide-divergence pair
ME TEM
ME vs TEM: by the numbers
- •TEM is the larger company ($7.33B vs $15M market cap).
- •Both run net losses; TEM's is the smaller (-22.20% vs -134.54% net margin).
- •TEM grew revenue faster over the past five years (42.06% vs -9.07% CAGR).
Metrics side by side
Valuation
| Metric | ME | TEM |
|---|---|---|
| P/S ratio | 0.10 | 5.45 |
| P/B ratio | 0.51 | 17.86 |
Profitability
| Metric | ME | TEM |
|---|---|---|
| Gross margin | 53.33% | 69.55% |
| Operating margin | -126.72% | -18.13% |
| Net margin | -134.54% | -22.20% |
| ROE | -721.75% | -72.74% |
| ROIC | -553.10% | -10.29% |
Growth (annualized)
| Metric | ME | TEM |
|---|---|---|
| Revenue CAGR (5Y) | -9.07% | 42.06% |
| Total return CAGR (5Y) | -68.93% | N/A |
Frequently asked
- Which has grown faster, ME or TEM?
- Over the past five years, TEM grew revenue faster — ME at a -9.07% CAGR versus TEM at 42.06%.
Go deeper
Dig into the metrics
23andMe P/E ratioTempus AI P/E ratio23andMe dividend yieldTempus AI dividend yield23andMe ROETempus AI ROE23andMe operating marginTempus AI operating margin23andMe revenue growthTempus AI revenue growth23andMe free cash flowTempus AI free cash flow
23andMe & Tempus AI appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 30, 2026.