23andMe Holding Co. (ME) vs Tempus AI, Inc. (TEM)
TEM leads on 6 of 8 compared metrics.
A side-by-side comparison of 23andMe Holding Co. and Tempus AI, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
Total return — ME vs TEM
growth of $100 · last 2yME -92.4%TEM +21.1%TEM compounded faster
Log scale — wide-divergence pair
ME TEM
ME vs TEM: by the numbers
- •TEM is the larger company ($8.35B vs $15M market cap).
- •Both run net losses; TEM's is the smaller (-22.20% vs -134.54% net margin).
- •TEM grew revenue faster over the past five years (42.06% vs -9.07% CAGR).
Which is better, ME or TEM?
Metric tally: ME 2 · TEM 6It depends on what you're optimizing for:
GrowthTEM(faster 5Y revenue CAGR)
QualityTEM(higher ROIC)
Valuation
| Metric | ME | TEM |
|---|---|---|
| P/S ratio | 0.10● | 6.27 |
| P/B ratio | 0.51● | 20.55 |
Profitability
| Metric | ME | TEM |
|---|---|---|
| Gross margin | 53.33% | 69.55%● |
| Operating margin | -114.00% | -18.13%● |
| Net margin | -134.54% | -22.20%● |
| ROE | -721.75% | -72.74%● |
| ROIC | -553.10% | -10.29%● |
Growth (annualized)
| Metric | ME | TEM |
|---|---|---|
| Revenue CAGR (5Y) | -9.07% | 42.06%● |
| Total return CAGR (5Y) | -68.93% | — |
Frequently asked
- Which is better, ME or TEM?
- It depends on your goal. growth: TEM (faster 5Y revenue CAGR); quality: TEM (higher ROIC). Across all compared metrics, TEM leads 6 to 2.
- Which has grown faster, ME or TEM?
- Over the past five years, TEM grew revenue faster — ME at a -9.07% CAGR versus TEM at 42.06%.
Go deeper
Dig into the metrics
23andMe P/E ratioTempus AI P/E ratio23andMe dividend yieldTempus AI dividend yield23andMe ROETempus AI ROE23andMe operating marginTempus AI operating margin23andMe revenue growthTempus AI revenue growth23andMe free cash flowTempus AI free cash flow
23andMe & Tempus AI appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.