Madrigal Pharmaceuticals, Inc. (MDGL) vs 10x Genomics, Inc. (TXG)

A side-by-side comparison of Madrigal Pharmaceuticals, Inc. and 10x Genomics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — MDGL vs TXG

growth of $100 · dividends reinvested · last 7y
MDGL +376.7% (+25.0%/yr)TXG +85.3% (+9.2%/yr)MDGL compounded faster over this window
0200400600Start $100202120232025$477$185
MDGL TXG

MDGL vs TXG: by the numbers

  • •MDGL is the larger company ($11.55B vs $10.54B market cap).
  • •Both run net losses; TXG's is the smaller (-12.18% vs -25.32% net margin).

Metrics side by side

Valuation

MetricMDGLTXG
P/S ratio9.0017.08
P/B ratio22.0612.76
FCF yieldN/A1.15%

Profitability

MetricMDGLTXG
Gross margin91.48%70.03%
Operating margin-25.13%-14.33%
Net margin-25.32%-12.18%
ROE-62.07%-9.10%
ROIC-37.02%-9.57%

Growth (annualized)

MetricMDGLTXG
Revenue CAGR (5Y)N/A8.74%
Total return CAGR (5Y)44.41%-7.24%

Frequently asked

How have MDGL and TXG total returns compared?
Over the past 5 years, MDGL delivered 44.41% and TXG delivered -7.24% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.