Which has the lower trailing P/E, MCK or SYK?

MCK has the lower trailing P/E: MCK trades at 22.26 and SYK at 33.75. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, MCK or SYK?

Over the past five years, MCK grew revenue faster — MCK at a 11.11% CAGR versus SYK at 9.72%.

Does MCK or SYK pay a bigger dividend?

MCK yields 0.38% and SYK yields 1.07% based on trailing dividends and the latest price.

Is MCK or SYK more profitable?

SYK runs the higher net margin — MCK at 1.18% versus SYK at 14.43%.

How have MCK and SYK total returns compared?

Over the past 10 years, MCK delivered 16.86% and SYK delivered 12.07% annualized total return. Past performance doesn't predict future results.

McKesson Corporation (MCK) vs Stryker Corporation (SYK)

A side-by-side comparison of McKesson Corporation and Stryker Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 3, 2026. Differences are shown without an overall score or investment verdict.

MCK

McKesson Corporation

$100.24B

$856.19HealthcareDelayed quote: Jul 31, 2026, 4:00 PM EDT

SYK

Stryker Corporation

$124.86B

$325.70HealthcareDelayed quote: Jul 31, 2026, 4:00 PM EDT

Total return — MCK vs SYK

growth of $100 · dividends reinvested · last 30y

MCK +4961.3%SYK +6840.2%SYK compounded faster

MCK SYK

MCK vs SYK: by the numbers

•SYK is the larger company ($124.86B vs $100.24B market cap).
•MCK trades at the lower trailing earnings multiple (22.26 vs 33.75 P/E), one valuation lens rather than an overall verdict.
•SYK converts more revenue to profit (14.43% vs 1.18% net margin).
•MCK grew revenue faster over the past five years (11.11% vs 9.72% CAGR).
•SYK pays the higher dividend yield (1.07% vs 0.38%).

Metrics side by side

Valuation

Metric	MCK	SYK
P/E ratio	22.26	33.75
Forward P/E	21.95	21.71
P/S ratio	0.26	4.87
P/B ratio	N/A	2.62
PEG ratio	0.46	5.16
EV / EBITDA	15.45	20.56
FCF yield	5.65%	3.74%

Profitability

Metric	MCK	SYK
Gross margin	3.61%	65.17%
Operating margin	1.58%	22.03%
Net margin	1.18%	14.43%
ROE	-219.24%	7.78%
ROIC	31.48%	8.53%

Dividends

Metric	MCK	SYK
Dividend yield	0.38%	1.07%
Payout ratio	8.51%	40.99%

Growth (annualized)

Metric	MCK	SYK
Revenue CAGR (5Y)	11.11%	9.72%
EPS CAGR (5Y)	40.71%	14.79%
FCF CAGR (5Y)	8.76%	9.60%
Total return CAGR (5Y)	33.96%	4.83%

Frequently asked

Which has the lower trailing P/E, MCK or SYK?: MCK has the lower trailing P/E: MCK trades at 22.26 and SYK at 33.75. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, MCK or SYK?: Over the past five years, MCK grew revenue faster — MCK at a 11.11% CAGR versus SYK at 9.72%.
Does MCK or SYK pay a bigger dividend?: MCK yields 0.38% and SYK yields 1.07% based on trailing dividends and the latest price.
Is MCK or SYK more profitable?: SYK runs the higher net margin — MCK at 1.18% versus SYK at 14.43%.
How have MCK and SYK total returns compared?: Over the past 10 years, MCK delivered 16.86% and SYK delivered 12.07% annualized total return. Past performance doesn't predict future results.

Go deeper

Full MCK analysis Full SYK analysis Interactive comparison tool

Dig into the metrics

McKesson P/E ratio Stryker P/E ratio McKesson dividend yield Stryker dividend yield McKesson ROE Stryker ROE McKesson operating margin Stryker operating margin McKesson revenue growth Stryker revenue growth McKesson free cash flow Stryker free cash flow

McKesson & Stryker appear in these rankings

Highest ROIC Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 3, 2026.