Which has the lower trailing P/E, MCK or SNY?

MCK has the lower trailing P/E: MCK trades at 23.83 and SNY at 80.55. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, MCK or SNY?

Over the past five years, MCK grew revenue faster — MCK at a 10.88% CAGR versus SNY at 4.96%.

Does MCK or SNY pay a bigger dividend?

MCK yields 0.37% and SNY yields 5.39% based on trailing dividends and the latest price.

Is MCK or SNY more profitable?

SNY runs the higher net margin — MCK at 1.12% versus SNY at 8.10%.

How have MCK and SNY total returns compared?

Over the past 10 years, MCK delivered 18.06% and SNY delivered 5.69% annualized total return. Past performance doesn't predict future results.

McKesson Corporation (MCK) vs Sanofi (SNY)

A side-by-side comparison of McKesson Corporation and Sanofi across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 28, 2026. Differences are shown without an overall score or investment verdict.

MCK

McKesson Corporation

$104.87B

$895.76HealthcareDelayed quote: Aug 28, 2026, 12:25 PM EDT

SNY

Sanofi

$107.47B

$44.76HealthcareDelayed quote: Aug 28, 2026, 12:25 PM EDT

Total return — MCK vs SNY

growth of $100 · dividends reinvested · last 10y

MCK +424.7% (+18.0%/yr)SNY +72.2% (+5.6%/yr)MCK compounded faster over this window

MCK SNY

MCK vs SNY: by the numbers

•SNY is the larger company ($107.47B vs $104.87B market cap).
•MCK trades at the lower trailing earnings multiple (23.83 vs 80.55 P/E), one valuation lens rather than an overall verdict.
•SNY converts more revenue to profit (8.10% vs 1.12% net margin).
•MCK grew revenue faster over the past five years (10.88% vs 4.96% CAGR).
•SNY pays the higher dividend yield (5.39% vs 0.37%).

Metrics side by side

Valuation

Metric	MCK	SNY
P/E ratio	23.83	80.55
Forward P/E	22.83	N/A
P/S ratio	0.26	1.89
P/B ratio	N/A	1.36
EV / EBITDA	15.18	10.17
FCF yield	5.83%	12.72%

Profitability

Metric	MCK	SNY
Gross margin	3.64%	73.01%
Operating margin	1.62%	14.74%
Net margin	1.12%	8.10%
ROE	-219.24%	5.82%
ROIC	28.34%	5.42%

Dividends

Metric	MCK	SNY
Dividend yield	0.37%	5.39%
Payout ratio	8.51%	64.36%

Growth (annualized)

Metric	MCK	SNY
Revenue CAGR (5Y)	10.88%	4.96%
EPS CAGR (5Y)	40.71%	-8.92%
FCF CAGR (5Y)	13.40%	12.83%
Total return CAGR (5Y)	35.40%	1.38%

Frequently asked

Which has the lower trailing P/E, MCK or SNY?: MCK has the lower trailing P/E: MCK trades at 23.83 and SNY at 80.55. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, MCK or SNY?: Over the past five years, MCK grew revenue faster — MCK at a 10.88% CAGR versus SNY at 4.96%.
Does MCK or SNY pay a bigger dividend?: MCK yields 0.37% and SNY yields 5.39% based on trailing dividends and the latest price.
Is MCK or SNY more profitable?: SNY runs the higher net margin — MCK at 1.12% versus SNY at 8.10%.
How have MCK and SNY total returns compared?: Over the past 10 years, MCK delivered 18.06% and SNY delivered 5.69% annualized total return. Past performance doesn't predict future results.

Go deeper

Full MCK analysis Full SNY analysis Interactive comparison tool

Dig into the metrics

McKesson P/E ratio Sanofi P/E ratio McKesson dividend yield Sanofi dividend yield McKesson ROE Sanofi ROE McKesson operating margin Sanofi operating margin McKesson revenue growth Sanofi revenue growth McKesson free cash flow Sanofi free cash flow

McKesson & Sanofi appear in these rankings

Highest Dividend Yield Stocks Highest ROIC Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 28, 2026.