McKesson Corporation (MCK) vs Regeneron Pharmaceuticals, Inc. (REGN)
A side-by-side comparison of McKesson Corporation and Regeneron Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 13, 2026. Differences are shown without an overall score or investment verdict.
MCK
McKesson Corporation
$878.30HealthcareDelayed quote: Sep 17, 2026, 12:35 PM EDT
REGN
Regeneron Pharmaceuticals, Inc.
$781.48HealthcareDelayed quote: Sep 17, 2026, 12:35 PM EDT
Total return — MCK vs REGN
growth of $100 · dividends reinvested · last 10yMCK +415.1% (+17.8%/yr)REGN +97.4% (+7.0%/yr)MCK compounded faster over this window
MCK REGN
MCK vs REGN: by the numbers
- •MCK is the larger company ($102.83B vs $80.51B market cap).
- •REGN trades at the lower trailing earnings multiple (19.33 vs 23.50 P/E), one valuation lens rather than an overall verdict.
- •REGN converts more revenue to profit (27.86% vs 1.12% net margin).
- •MCK grew revenue faster over the past five years (10.88% vs 4.64% CAGR).
- •REGN pays the higher dividend yield (0.47% vs 0.37%).
Metrics side by side
Valuation
| Metric | MCK | REGN |
|---|---|---|
| P/E ratio | 23.50 | 19.33 |
| Forward P/E | 19.68 | 14.34 |
| P/S ratio | 0.25 | 5.18 |
| P/B ratio | N/A | 2.54 |
| EV / EBITDA | 14.74 | 17.79 |
| FCF yield | 6.01% | 4.37% |
Profitability
| Metric | MCK | REGN |
|---|---|---|
| Gross margin | 3.64% | 84.86% |
| Operating margin | 1.62% | 25.56% |
| Net margin | 1.12% | 27.86% |
| ROE | N/A | 13.65% |
| ROIC | 28.34% | 9.19% |
Dividends
| Metric | MCK | REGN |
|---|---|---|
| Dividend yield | 0.37% | 0.47% |
| Payout ratio | 8.78% | 9.15% |
Growth (annualized)
| Metric | MCK | REGN |
|---|---|---|
| Revenue CAGR (5Y) | 10.88% | 4.64% |
| EPS CAGR (5Y) | 40.71% | 5.70% |
| FCF CAGR (5Y) | 13.40% | 15.77% |
| Total return CAGR (5Y) | 34.85% | 3.93% |
Frequently asked
- Which has the lower trailing P/E, MCK or REGN?
- REGN has the lower trailing P/E: MCK trades at 23.50 and REGN at 19.33. P/E is one valuation measure and does not by itself establish which business is cheaper.
- Which has grown faster, MCK or REGN?
- Over the past five years, MCK grew revenue faster — MCK at a 10.88% CAGR versus REGN at 4.64%.
- Does MCK or REGN pay a bigger dividend?
- MCK yields 0.37% and REGN yields 0.47% based on trailing dividends and the latest price.
- Is MCK or REGN more profitable?
- REGN runs the higher net margin — MCK at 1.12% versus REGN at 27.86%.
- How have MCK and REGN total returns compared?
- Over the past 10 years, MCK delivered 18.37% and REGN delivered 7.45% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
McKesson P/E ratioRegeneron Pharmaceuticals P/E ratioMcKesson dividend yieldRegeneron Pharmaceuticals dividend yieldMcKesson ROERegeneron Pharmaceuticals ROEMcKesson operating marginRegeneron Pharmaceuticals operating marginMcKesson revenue growthRegeneron Pharmaceuticals revenue growthMcKesson free cash flowRegeneron Pharmaceuticals free cash flow
McKesson & Regeneron Pharmaceuticals appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 13, 2026.