McKesson Corporation (MCK) vs Regeneron Pharmaceuticals, Inc. (REGN)

REGN leads on 9 of 15 compared metrics.

A side-by-side comparison of McKesson Corporation and Regeneron Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 19, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Compare

Total return — MCK vs REGN

growth of $100 · last 30y
MCK +3003.1%REGN +3740.9%REGN compounded faster
02k4k6k8kStart $100200120062011201620212026$3,103$3,841
MCK REGN

MCK vs REGN: by the numbers

  • MCK is the larger company ($87.88B vs $62.84B market cap).
  • REGN trades at the lower earnings multiple (14.86 vs 19.51 P/E).
  • REGN converts more revenue to profit (29.65% vs 1.18% net margin).
  • MCK grew revenue faster over the past five years (11.11% vs 10.16% CAGR).
  • REGN pays the higher dividend yield (0.60% vs 0.44%).

Which is better, MCK or REGN?

Metric tally: MCK 6 · REGN 9

It depends on what you're optimizing for:

ValueREGN(lower P/E)
GrowthMCK(faster 5Y revenue CAGR)
IncomeREGN(higher dividend yield)
QualityMCK(higher ROIC)

Metrics side by side

Valuation

MetricMCKREGN
P/E ratio19.5114.86
Forward P/E14.9011.26
P/S ratio0.234.40
P/B ratio2.09
PEG ratio0.463.38
EV / EBITDA13.7911.39
FCF yield6.44%6.33%

Profitability

MetricMCKREGN
Gross margin3.61%84.55%
Operating margin1.58%24.32%
Net margin1.18%29.65%
ROE-219.24%14.08%
ROIC31.48%8.51%

Dividends

MetricMCKREGN
Dividend yield0.44%0.60%
Payout ratio8.51%8.45%

Growth (annualized)

MetricMCKREGN
Revenue CAGR (5Y)11.11%10.16%
EPS CAGR (5Y)40.71%5.70%
FCF CAGR (5Y)8.76%15.42%
Total return CAGR (5Y)33.07%2.71%

Frequently asked

Which is better, MCK or REGN?
It depends on your goal. value: REGN (lower P/E); growth: MCK (faster 5Y revenue CAGR); income: REGN (higher dividend yield); quality: MCK (higher ROIC). Across all compared metrics, REGN leads 9 to 6.
Is MCK or REGN cheaper?
On trailing earnings, REGN is cheaper: MCK trades at a 19.51 P/E and REGN at 14.86.
Which has grown faster, MCK or REGN?
Over the past five years, MCK grew revenue faster — MCK at a 11.11% CAGR versus REGN at 10.16%.
Does MCK or REGN pay a bigger dividend?
MCK yields 0.44% and REGN yields 0.60% based on trailing dividends and the latest price.
Is MCK or REGN more profitable?
REGN runs the higher net margin — MCK at 1.18% versus REGN at 29.65%.
Which has been the better investment, MCK or REGN?
Over the past 10-year, MCK delivered the higher annualized total return — MCK at 16.38% versus REGN at 5.67%. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 19, 2026.