McKesson Corporation (MCK) vs Regeneron Pharmaceuticals, Inc. (REGN)
A side-by-side comparison of McKesson Corporation and Regeneron Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 3, 2026. Differences are shown without an overall score or investment verdict.
MCK
McKesson Corporation
$852.35HealthcareDelayed quote: Aug 3, 2026, 11:10 AM EDT
REGN
Regeneron Pharmaceuticals, Inc.
$765.40HealthcareDelayed quote: Aug 3, 2026, 11:10 AM EDT
Total return — MCK vs REGN
growth of $100 · dividends reinvested · last 30yMCK +4961.3%REGN +4818.8%MCK compounded faster
MCK REGN
MCK vs REGN: by the numbers
- •MCK is the larger company ($99.79B vs $78.85B market cap).
- •REGN trades at the lower trailing earnings multiple (18.86 vs 22.26 P/E), one valuation lens rather than an overall verdict.
- •REGN converts more revenue to profit (27.86% vs 1.18% net margin).
- •MCK grew revenue faster over the past five years (11.11% vs 4.64% CAGR).
- •REGN pays the higher dividend yield (0.48% vs 0.38%).
Metrics side by side
Valuation
| Metric | MCK | REGN |
|---|---|---|
| P/E ratio | 22.26 | 18.86 |
| Forward P/E | 21.95 | 14.49 |
| P/S ratio | 0.26 | 5.24 |
| P/B ratio | N/A | 2.10 |
| PEG ratio | 0.46 | 3.38 |
| EV / EBITDA | 15.45 | 18.16 |
| FCF yield | 5.65% | 4.32% |
Profitability
| Metric | MCK | REGN |
|---|---|---|
| Gross margin | 3.61% | 84.86% |
| Operating margin | 1.58% | 25.56% |
| Net margin | 1.18% | 27.86% |
| ROE | -219.24% | 11.15% |
| ROIC | 31.48% | 8.51% |
Dividends
| Metric | MCK | REGN |
|---|---|---|
| Dividend yield | 0.38% | 0.48% |
| Payout ratio | 8.51% | 8.45% |
Growth (annualized)
| Metric | MCK | REGN |
|---|---|---|
| Revenue CAGR (5Y) | 11.11% | 4.64% |
| EPS CAGR (5Y) | 40.71% | 5.70% |
| FCF CAGR (5Y) | 8.76% | 15.77% |
| Total return CAGR (5Y) | 33.96% | 5.99% |
Frequently asked
- Which has the lower trailing P/E, MCK or REGN?
- REGN has the lower trailing P/E: MCK trades at 22.26 and REGN at 18.86. P/E is one valuation measure and does not by itself establish which business is cheaper.
- Which has grown faster, MCK or REGN?
- Over the past five years, MCK grew revenue faster — MCK at a 11.11% CAGR versus REGN at 4.64%.
- Does MCK or REGN pay a bigger dividend?
- MCK yields 0.38% and REGN yields 0.48% based on trailing dividends and the latest price.
- Is MCK or REGN more profitable?
- REGN runs the higher net margin — MCK at 1.18% versus REGN at 27.86%.
- How have MCK and REGN total returns compared?
- Over the past 10 years, MCK delivered 16.86% and REGN delivered 6.10% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
McKesson P/E ratioRegeneron Pharmaceuticals P/E ratioMcKesson dividend yieldRegeneron Pharmaceuticals dividend yieldMcKesson ROERegeneron Pharmaceuticals ROEMcKesson operating marginRegeneron Pharmaceuticals operating marginMcKesson revenue growthRegeneron Pharmaceuticals revenue growthMcKesson free cash flowRegeneron Pharmaceuticals free cash flow
McKesson & Regeneron Pharmaceuticals appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 3, 2026.