McKesson Corporation (MCK) vs Regeneron Pharmaceuticals, Inc. (REGN)
REGN leads on 9 of 15 compared metrics.
A side-by-side comparison of McKesson Corporation and Regeneron Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 19, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
MCK
McKesson Corporation
$750.63Healthcare
REGN
Regeneron Pharmaceuticals, Inc.
$609.94Healthcare
Total return — MCK vs REGN
growth of $100 · last 30yMCK +3003.1%REGN +3740.9%REGN compounded faster
MCK REGN
MCK vs REGN: by the numbers
- •MCK is the larger company ($87.88B vs $62.84B market cap).
- •REGN trades at the lower earnings multiple (14.86 vs 19.51 P/E).
- •REGN converts more revenue to profit (29.65% vs 1.18% net margin).
- •MCK grew revenue faster over the past five years (11.11% vs 10.16% CAGR).
- •REGN pays the higher dividend yield (0.60% vs 0.44%).
Which is better, MCK or REGN?
Metric tally: MCK 6 · REGN 9It depends on what you're optimizing for:
ValueREGN(lower P/E)
GrowthMCK(faster 5Y revenue CAGR)
IncomeREGN(higher dividend yield)
QualityMCK(higher ROIC)
Metrics side by side
Valuation
| Metric | MCK | REGN |
|---|---|---|
| P/E ratio | 19.51 | 14.86● |
| Forward P/E | 14.90 | 11.26● |
| P/S ratio | 0.23● | 4.40 |
| P/B ratio | — | 2.09 |
| PEG ratio | 0.46● | 3.38 |
| EV / EBITDA | 13.79 | 11.39● |
| FCF yield | 6.44% | 6.33% |
Profitability
| Metric | MCK | REGN |
|---|---|---|
| Gross margin | 3.61% | 84.55%● |
| Operating margin | 1.58% | 24.32%● |
| Net margin | 1.18% | 29.65%● |
| ROE | -219.24% | 14.08%● |
| ROIC | 31.48%● | 8.51% |
Dividends
| Metric | MCK | REGN |
|---|---|---|
| Dividend yield | 0.44% | 0.60%● |
| Payout ratio | 8.51% | 8.45% |
Growth (annualized)
| Metric | MCK | REGN |
|---|---|---|
| Revenue CAGR (5Y) | 11.11%● | 10.16% |
| EPS CAGR (5Y) | 40.71%● | 5.70% |
| FCF CAGR (5Y) | 8.76% | 15.42%● |
| Total return CAGR (5Y) | 33.07%● | 2.71% |
Frequently asked
- Which is better, MCK or REGN?
- It depends on your goal. value: REGN (lower P/E); growth: MCK (faster 5Y revenue CAGR); income: REGN (higher dividend yield); quality: MCK (higher ROIC). Across all compared metrics, REGN leads 9 to 6.
- Is MCK or REGN cheaper?
- On trailing earnings, REGN is cheaper: MCK trades at a 19.51 P/E and REGN at 14.86.
- Which has grown faster, MCK or REGN?
- Over the past five years, MCK grew revenue faster — MCK at a 11.11% CAGR versus REGN at 10.16%.
- Does MCK or REGN pay a bigger dividend?
- MCK yields 0.44% and REGN yields 0.60% based on trailing dividends and the latest price.
- Is MCK or REGN more profitable?
- REGN runs the higher net margin — MCK at 1.18% versus REGN at 29.65%.
- Which has been the better investment, MCK or REGN?
- Over the past 10-year, MCK delivered the higher annualized total return — MCK at 16.38% versus REGN at 5.67%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
McKesson P/E ratioRegeneron Pharmaceuticals P/E ratioMcKesson dividend yieldRegeneron Pharmaceuticals dividend yieldMcKesson ROERegeneron Pharmaceuticals ROEMcKesson operating marginRegeneron Pharmaceuticals operating marginMcKesson revenue growthRegeneron Pharmaceuticals revenue growthMcKesson free cash flowRegeneron Pharmaceuticals free cash flow
McKesson & Regeneron Pharmaceuticals appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 19, 2026.