Lyell Immunopharma, Inc. (LYEL) vs Cartesian Therapeutics, Inc. (RNAC)

A side-by-side comparison of Lyell Immunopharma, Inc. and Cartesian Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — LYEL vs RNAC

growth of $100 · dividends reinvested · last 5y
LYEL -97.3% (-51.5%/yr)RNAC -95.1% (-45.4%/yr)RNAC compounded faster over this window
020406080100Start $10020222023202420252026$3$5
LYEL RNAC

LYEL vs RNAC: by the numbers

  • •LYEL is the larger company ($211M vs $198M market cap).
  • •Both run net losses; RNAC's is the smaller (-10422.48% vs -920285.19% net margin).
  • •Both shrank revenue over the past five years; RNAC's decline was smaller (-50.01% vs -68.32% CAGR).

Metrics side by side

Valuation

MetricLYELRNAC
P/S ratio7814.17134.28
P/B ratio0.90N/A

Profitability

MetricLYELRNAC
Gross margin-31952.78%100.00%
Operating margin-566038.89%-3099.93%
Net margin-920285.19%-10422.48%
ROE-106.27%N/A
ROIC-70.80%-33.10%

Growth (annualized)

MetricLYELRNAC
Revenue CAGR (5Y)-68.32%-50.01%
Total return CAGR (5Y)-48.18%-44.03%

Frequently asked

Which has grown faster, LYEL or RNAC?
Neither grew: over the past five years both shrank revenue, with RNAC's decline the smaller — LYEL at a -68.32% CAGR versus RNAC at -50.01%.
How have LYEL and RNAC total returns compared?
Over the past 5 years, LYEL delivered -48.18% and RNAC delivered -44.03% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.