Which has grown faster, LYEL or NAGE?

Over the past five years, NAGE grew revenue faster — LYEL at a -68.32% CAGR versus NAGE at 15.80%.

Is LYEL or NAGE more profitable?

NAGE runs the higher net margin — LYEL at -920285.19% versus NAGE at 12.39%.

How have LYEL and NAGE total returns compared?

Over the past 5 years, LYEL delivered -48.18% and NAGE delivered -15.72% annualized total return. Past performance doesn't predict future results.

Lyell Immunopharma, Inc. (LYEL) vs Niagen Bioscience Inc (NAGE)

A side-by-side comparison of Lyell Immunopharma, Inc. and Niagen Bioscience Inc across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

LYEL

Lyell Immunopharma, Inc.

$215M

$8.77HealthcareDelayed quote: Oct 6, 2026, 11:05 AM EDT

NAGE

Niagen Bioscience Inc

$215M

$2.70HealthcareDelayed quote: Oct 6, 2026, 11:05 AM EDT

Total return — LYEL vs NAGE

growth of $100 · dividends reinvested · last 5y

LYEL -97.3% (-51.5%/yr)NAGE -73.0% (-23.1%/yr)NAGE compounded faster over this window

Log scale — wide-divergence pair

LYEL NAGE

LYEL vs NAGE: by the numbers

•LYEL is the larger company ($215M vs $215M market cap).
•NAGE is profitable (12.39% net margin) while LYEL runs a net loss (-920285.19%).
•NAGE grew revenue faster over the past five years (15.80% vs -68.32% CAGR).

Metrics side by side

Valuation

Metric	LYEL	NAGE
P/E ratio	N/A	14.46
Forward P/E	N/A	18.69
P/S ratio	7959.38	1.66
P/B ratio	0.92	2.60
EV / EBITDA	N/A	14.40
FCF yield	N/A	2.64%

Profitability

Metric	LYEL	NAGE
Gross margin	-31952.78%	64.24%
Operating margin	-566038.89%	6.67%
Net margin	-920285.19%	12.39%
ROE	-106.27%	19.38%
ROIC	-70.80%	8.84%

Growth (annualized)

Metric	LYEL	NAGE
Revenue CAGR (5Y)	-68.32%	15.80%
Total return CAGR (5Y)	-48.18%	-15.72%

Frequently asked

Which has grown faster, LYEL or NAGE?: Over the past five years, NAGE grew revenue faster — LYEL at a -68.32% CAGR versus NAGE at 15.80%.
Is LYEL or NAGE more profitable?: NAGE runs the higher net margin — LYEL at -920285.19% versus NAGE at 12.39%.
How have LYEL and NAGE total returns compared?: Over the past 5 years, LYEL delivered -48.18% and NAGE delivered -15.72% annualized total return. Past performance doesn't predict future results.

Go deeper

Full LYEL analysis Full NAGE analysis Interactive comparison tool

Dig into the metrics

Niagen Bioscience P/E ratio Lyell Immunopharma ROE Niagen Bioscience ROE Lyell Immunopharma operating margin Niagen Bioscience operating margin Lyell Immunopharma revenue growth Niagen Bioscience revenue growth Lyell Immunopharma free cash flow Niagen Bioscience free cash flow

Lyell Immunopharma & Niagen Bioscience appear in these rankings

Fastest Revenue Growth Stocks Lowest P/E Ratio Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.