Lexicon Pharmaceuticals, Inc. (LXRX) vs Pacific Biosciences of California, Inc. (PACB)
A side-by-side comparison of Lexicon Pharmaceuticals, Inc. and Pacific Biosciences of California, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
LXRX
Lexicon Pharmaceuticals, Inc.
$1.75HealthcareDelayed quote: Oct 6, 2026, 12:24 PM EDT
PACB
Pacific Biosciences of California, Inc.
$2.69HealthcareDelayed quote: Oct 6, 2026, 12:25 PM EDT
Total return — LXRX vs PACB
growth of $100 · dividends reinvested · last 10yLXRX -90.4% (-20.9%/yr)PACB -68.1% (-10.8%/yr)PACB compounded faster over this window
LXRX PACB
LXRX vs PACB: by the numbers
- •PACB is the larger company ($835M vs $775M market cap).
- •Both run net losses; PACB's is the smaller (-82.49% vs -147.38% net margin).
- •LXRX grew revenue faster over the past five years (42.36% vs 8.52% CAGR).
Metrics side by side
Valuation
| Metric | LXRX | PACB |
|---|---|---|
| P/S ratio | 18.69 | 5.24 |
| P/B ratio | 4.44 | N/A |
Profitability
| Metric | LXRX | PACB |
|---|---|---|
| Gross margin | 98.85% | 35.97% |
| Operating margin | -98.21% | -348.46% |
| Net margin | -147.38% | -82.49% |
| ROE | -35.02% | N/A |
| ROIC | -23.16% | -23.80% |
Growth (annualized)
| Metric | LXRX | PACB |
|---|---|---|
| Revenue CAGR (5Y) | 42.36% | 8.52% |
| Total return CAGR (5Y) | -18.54% | -35.20% |
Frequently asked
- Which has grown faster, LXRX or PACB?
- Over the past five years, LXRX grew revenue faster — LXRX at a 42.36% CAGR versus PACB at 8.52%.
- How have LXRX and PACB total returns compared?
- Over the past 10 years, LXRX delivered -21.03% and PACB delivered -10.80% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Lexicon Pharmaceuticals ROEPacific Biosciences of California ROELexicon Pharmaceuticals operating marginPacific Biosciences of California operating marginLexicon Pharmaceuticals revenue growthPacific Biosciences of California revenue growthLexicon Pharmaceuticals free cash flowPacific Biosciences of California free cash flow
Lexicon Pharmaceuticals & Pacific Biosciences of California appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.