How have LONA and TXMD total returns compared?

Over the past 5 years, LONA delivered -43.13% and TXMD delivered -44.16% annualized total return. Past performance doesn't predict future results.

LeonaBio, Inc. (LONA) vs TherapeuticsMD, Inc. (TXMD)

A side-by-side comparison of LeonaBio, Inc. and TherapeuticsMD, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

LONA

LeonaBio, Inc.

$23M

$5.75HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

TXMD

TherapeuticsMD, Inc.

$23M

$2.02HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — LONA vs TXMD

growth of $100 · dividends reinvested · last 6y

LONA -96.7% (-43.5%/yr)TXMD -97.2% (-45.0%/yr)LONA compounded faster over this window

LONA TXMD

LONA vs TXMD: by the numbers

•TXMD is the larger company ($23M vs $23M market cap).
•Both run net losses; LONA's is the smaller (0.00% vs -6.64% net margin).

Metrics side by side

Valuation

Metric	LONA	TXMD
Forward P/E	N/A	11.88
P/S ratio	N/A	7.15
P/B ratio	0.68	0.86
FCF yield	N/A	13.34%

Profitability

Metric	LONA	TXMD
Gross margin	0.00%	100.00%
Operating margin	0.00%	-139.44%
Net margin	0.00%	-6.64%
ROE	-421.06%	-0.80%
ROIC	-248.21%	-11.84%

Growth (annualized)

Metric	LONA	TXMD
Revenue CAGR (5Y)	N/A	-47.86%
Total return CAGR (5Y)	-43.13%	-44.16%

Frequently asked

How have LONA and TXMD total returns compared?: Over the past 5 years, LONA delivered -43.13% and TXMD delivered -44.16% annualized total return. Past performance doesn't predict future results.

Go deeper

Full LONA analysis Full TXMD analysis Interactive comparison tool

Dig into the metrics

LeonaBio ROE TherapeuticsMD ROE LeonaBio operating margin TherapeuticsMD operating margin LeonaBio revenue growth TherapeuticsMD revenue growth LeonaBio free cash flow TherapeuticsMD free cash flow

LeonaBio & TherapeuticsMD appear in these rankings

Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.