Which has grown faster, LNTH or RYTM?

Over the past five years, RYTM grew revenue faster — LNTH at a 32.84% CAGR versus RYTM at 278.53%.

Is LNTH or RYTM more profitable?

LNTH runs the higher net margin — LNTH at 17.69% versus RYTM at -85.59%.

How have LNTH and RYTM total returns compared?

Over the past 5 years, LNTH delivered 31.73% and RYTM delivered 49.95% annualized total return. Past performance doesn't predict future results.

Lantheus Holdings, Inc. (LNTH) vs Rhythm Pharmaceuticals, Inc. (RYTM)

A side-by-side comparison of Lantheus Holdings, Inc. and Rhythm Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

LNTH

Lantheus Holdings, Inc.

$6.51B

$99.95HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

RYTM

Rhythm Pharmaceuticals, Inc.

$6.23B

$90.77HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — LNTH vs RYTM

growth of $100 · dividends reinvested · last 9y

LNTH +456.6% (+21.0%/yr)RYTM +208.2% (+13.3%/yr)LNTH compounded faster over this window

LNTH RYTM

LNTH vs RYTM: by the numbers

•LNTH is the larger company ($6.51B vs $6.23B market cap).
•LNTH is profitable (17.69% net margin) while RYTM runs a net loss (-85.59%).
•RYTM grew revenue faster over the past five years (278.53% vs 32.84% CAGR).

Metrics side by side

Valuation

Metric	LNTH	RYTM
P/E ratio	24.14	N/A
Forward P/E	18.46	N/A
P/S ratio	4.18	25.95
P/B ratio	4.96	60.46
EV / EBITDA	16.99	N/A
FCF yield	5.96%	N/A

Profitability

Metric	LNTH	RYTM
Gross margin	60.14%	89.00%
Operating margin	19.43%	-101.19%
Net margin	17.69%	-85.59%
ROE	20.99%	-94.50%
ROIC	11.03%	-63.96%

Growth (annualized)

Metric	LNTH	RYTM
Revenue CAGR (5Y)	32.84%	278.53%
FCF CAGR (5Y)	59.88%	N/A
Total return CAGR (5Y)	31.73%	49.95%

Frequently asked

Which has grown faster, LNTH or RYTM?: Over the past five years, RYTM grew revenue faster — LNTH at a 32.84% CAGR versus RYTM at 278.53%.
Is LNTH or RYTM more profitable?: LNTH runs the higher net margin — LNTH at 17.69% versus RYTM at -85.59%.
How have LNTH and RYTM total returns compared?: Over the past 5 years, LNTH delivered 31.73% and RYTM delivered 49.95% annualized total return. Past performance doesn't predict future results.

Go deeper

Full LNTH analysis Full RYTM analysis Interactive comparison tool

Dig into the metrics

Lantheus P/E ratio Lantheus ROE Rhythm Pharmaceuticals ROE Lantheus operating margin Rhythm Pharmaceuticals operating margin Lantheus revenue growth Rhythm Pharmaceuticals revenue growth Lantheus free cash flow Rhythm Pharmaceuticals free cash flow

Lantheus & Rhythm Pharmaceuticals appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.