Eli Lilly and Company (LLY) vs State Street SPDR S&P 500 ETF (SPY)
Over the past 10 years, LLY outperformed SPY — 32.58% vs 15.36% annualized total return (price plus dividends).
A side-by-side comparison of Eli Lilly and Company and State Street SPDR S&P 500 ETF across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 11, 2026. Differences are shown without an overall score or investment verdict.
Total return — LLY vs SPY
growth of $100 · dividends reinvested · last 10yMetrics side by side
Did LLY beat SPY?
Over the past 10 years, LLY outperformed SPY — 32.58% vs 15.36% annualized total return (price plus dividends).
Total return (annualized)
| Metric | LLY | SPY |
|---|---|---|
| Total return (1Y) | 49.81% | 17.49% |
| Total return CAGR (3Y) | 24.98% | 20.82% |
| Total return CAGR (5Y) | 37.46% | 12.73% |
| Total return CAGR (10Y) | 32.58% | 15.36% |
SPY is an index fund, so valuation, profitability, and per-company growth metrics don't apply — the head-to-head here is total return (price plus reinvested dividends).
Frequently asked
- Has LLY beaten SPY?
- Over the past 10 years, LLY outperformed SPY — 32.58% vs 15.36% annualized total return (price plus dividends).
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 11, 2026.