Eli Lilly and Company (LLY) vs State Street SPDR S&P 500 ETF Trust (SPY)

Over the past 10 years, LLY outperformed SPY — 33.50% vs 15.31% annualized total return (price plus dividends).

A side-by-side comparison of Eli Lilly and Company and State Street SPDR S&P 500 ETF Trust across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Total return — LLY vs SPY

growth of $100 · last 30y
LLY +3454.0%SPY +1003.5%LLY compounded faster
01k2k3kStart $100200120062011201620212026$3,554$1,103
LLY SPY

Did LLY beat SPY?

Over the past 10 years, LLY outperformed SPY — 33.50% vs 15.31% annualized total return (price plus dividends).

Total return (annualized)

MetricLLYSPY
Total return (1Y)40.54%24.28%
Total return CAGR (3Y)37.48%21.12%
Total return CAGR (5Y)39.57%13.36%
Total return CAGR (10Y)33.50%15.31%

SPY is an index fund, so valuation, profitability, and per-company growth metrics don't apply — the head-to-head here is total return (price plus reinvested dividends).

Frequently asked

Has LLY beaten SPY?
Over the past 10 years, LLY outperformed SPY — 33.50% vs 15.31% annualized total return (price plus dividends).

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.