Eli Lilly and Company (LLY) vs Microsoft Corporation (MSFT)
A side-by-side comparison of Eli Lilly and Company and Microsoft Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 28, 2026. Differences are shown without an overall score or investment verdict.
Different business models: LLY is classified in Healthcare; MSFT is classified in Technology. Margin, capital intensity, and valuation differences should be interpreted in that sector context.
LLY
Eli Lilly and Company
$1,222.61HealthcareDelayed quote: Jul 28, 2026, 4:00 PM EDT
MSFT
Microsoft Corporation
$393.35TechnologyDelayed quote: Jul 28, 2026, 4:00 PM EDT
Total return — LLY vs MSFT
growth of $100 · dividends reinvested · last 30yLLY +8631.2%MSFT +7530.9%LLY compounded faster
LLY MSFT
LLY vs MSFT: by the numbers
- •MSFT is the larger company ($2.92T vs $1.15T market cap).
- •MSFT trades at the lower trailing earnings multiple (23.16 vs 42.54 P/E), one valuation lens rather than an overall verdict.
- •MSFT converts more revenue to profit (39.34% vs 34.98% net margin).
- •LLY grew revenue faster over the past five years (23.17% vs 14.75% CAGR).
- •MSFT pays the higher dividend yield (0.91% vs 0.54%).
Metrics side by side
Valuation
| Metric | LLY | MSFT |
|---|---|---|
| P/E ratio | 42.54 | 23.16 |
| Forward P/E | 34.10 | 22.87 |
| P/S ratio | 14.85 | 9.10 |
| P/B ratio | 34.39 | 6.99 |
| PEG ratio | 0.49 | 2.34 |
| EV / EBITDA | 31.98 | 15.53 |
| FCF yield | 1.27% | 2.52% |
Profitability
| Metric | LLY | MSFT |
|---|---|---|
| Gross margin | 83.51% | 68.31% |
| Operating margin | 45.87% | 46.80% |
| Net margin | 34.98% | 39.34% |
| ROE | 81.01% | 30.22% |
| ROIC | 30.20% | 21.63% |
Dividends
| Metric | LLY | MSFT |
|---|---|---|
| Dividend yield | 0.54% | 0.91% |
| Payout ratio | 28.09% | 25.99% |
Growth (annualized)
| Metric | LLY | MSFT |
|---|---|---|
| Revenue CAGR (5Y) | 23.17% | 14.75% |
| EPS CAGR (5Y) | 28.88% | 18.68% |
| FCF CAGR (5Y) | 19.54% | 6.27% |
| Total return CAGR (5Y) | 38.81% | 7.19% |
Frequently asked
- Which has the lower trailing P/E, LLY or MSFT?
- MSFT has the lower trailing P/E: LLY trades at 42.54 and MSFT at 23.16. P/E is one valuation measure and does not by itself establish which business is cheaper.
- Which has grown faster, LLY or MSFT?
- Over the past five years, LLY grew revenue faster — LLY at a 23.17% CAGR versus MSFT at 14.75%.
- Does LLY or MSFT pay a bigger dividend?
- LLY yields 0.54% and MSFT yields 0.91% based on trailing dividends and the latest price.
- Is LLY or MSFT more profitable?
- MSFT runs the higher net margin — LLY at 34.98% versus MSFT at 39.34%.
- How have LLY and MSFT total returns compared?
- Over the past 10 years, LLY delivered 32.66% and MSFT delivered 22.86% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Eli Lilly and P/E ratioMicrosoft P/E ratioEli Lilly and dividend yieldMicrosoft dividend yieldEli Lilly and ROEMicrosoft ROEEli Lilly and operating marginMicrosoft operating marginEli Lilly and revenue growthMicrosoft revenue growthEli Lilly and free cash flowMicrosoft free cash flow
Eli Lilly and & Microsoft appear in these rankings
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Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 28, 2026.