Eli Lilly and Company (LLY) vs Merck & Co., Inc. (MRK)

A side-by-side comparison of Eli Lilly and Company and Merck & Co., Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 11, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnLLY vs MRK

growth of $100 · dividends reinvested · last 10y
LLY +1566.6% (+32.5%/yr)MRK +228.7% (+12.6%/yr)LLY compounded faster over this window
Log scale — wide-divergence pair
101001k10kStart $10020182020202220242026$1,667$329
LLY MRK

LLY vs MRK: by the numbers

  • LLY is the larger company ($1.05T vs $355.49B market cap).
  • LLY trades at the lower trailing earnings multiple (37.42 vs 115.15 P/E), one valuation lens rather than an overall verdict.
  • LLY converts more revenue to profit (33.53% vs 4.78% net margin).
  • LLY grew revenue faster over the past five years (24.42% vs 7.87% CAGR).
  • MRK pays the higher dividend yield (2.32% vs 0.60%).

Metrics side by side

Valuation

MetricLLYMRK
P/E ratio37.42115.15
Forward P/E30.6452.41
P/S ratio13.185.35
P/B ratio31.008.48
EV / EBITDA29.9122.76
FCF yield1.91%4.52%

Profitability

MetricLLYMRK
Gross margin84.01%75.38%
Operating margin43.92%36.17%
Net margin33.53%4.78%
ROE78.84%7.57%
ROIC27.38%5.80%

Dividends

MetricLLYMRK
Dividend yield0.60%2.32%
Payout ratio22.45%268.80%

Growth (annualized)

MetricLLYMRK
Revenue CAGR (5Y)24.42%7.87%
EPS CAGR (5Y)28.88%21.21%
FCF CAGR (5Y)32.91%23.61%
Total return CAGR (5Y)37.46%18.15%

Frequently asked

Which has the lower trailing P/E, LLY or MRK?
LLY has the lower trailing P/E: LLY trades at 37.42 and MRK at 115.15. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, LLY or MRK?
Over the past five years, LLY grew revenue faster — LLY at a 24.42% CAGR versus MRK at 7.87%.
Does LLY or MRK pay a bigger dividend?
LLY yields 0.60% and MRK yields 2.32% based on trailing dividends and the latest price.
Is LLY or MRK more profitable?
LLY runs the higher net margin — LLY at 33.53% versus MRK at 4.78%.
How have LLY and MRK total returns compared?
Over the past 10 years, LLY delivered 32.58% and MRK delivered 12.68% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 11, 2026.