Which has the lower trailing P/E, LGND or LNTH?

LNTH has the lower trailing P/E: LGND trades at 31.72 and LNTH at 24.14. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, LGND or LNTH?

Over the past five years, LNTH grew revenue faster — LGND at a 2.92% CAGR versus LNTH at 32.84%.

Is LGND or LNTH more profitable?

LGND runs the higher net margin — LGND at 67.88% versus LNTH at 17.69%.

How have LGND and LNTH total returns compared?

Over the past 10 years, LGND delivered 17.12% and LNTH delivered 28.40% annualized total return. Past performance doesn't predict future results.

Ligand Pharmaceuticals Incorporated (LGND) vs Lantheus Holdings, Inc. (LNTH)

A side-by-side comparison of Ligand Pharmaceuticals Incorporated and Lantheus Holdings, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

LGND

Ligand Pharmaceuticals Incorporated

$5.94B

$296.57HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT

LNTH

Lantheus Holdings, Inc.

$6.51B

$99.96HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT

Total return — LGND vs LNTH

growth of $100 · dividends reinvested · last 10y

LGND +389.0% (+17.2%/yr)LNTH +1121.8% (+28.4%/yr)LNTH compounded faster over this window

LGND LNTH

LGND vs LNTH: by the numbers

•LNTH is the larger company ($6.51B vs $5.94B market cap).
•LNTH trades at the lower trailing earnings multiple (24.14 vs 31.72 P/E), one valuation lens rather than an overall verdict.
•LGND converts more revenue to profit (67.88% vs 17.69% net margin).
•LNTH grew revenue faster over the past five years (32.84% vs 2.92% CAGR).

Metrics side by side

Valuation

Metric	LGND	LNTH
P/E ratio	31.72	24.14
Forward P/E	31.87	18.46
P/S ratio	20.46	4.18
P/B ratio	6.14	4.96
EV / EBITDA	44.96	16.99
FCF yield	2.21%	5.96%

Profitability

Metric	LGND	LNTH
Gross margin	98.58%	60.14%
Operating margin	17.61%	19.43%
Net margin	67.88%	17.69%
ROE	20.38%	20.99%
ROIC	3.91%	11.03%

Growth (annualized)

Metric	LGND	LNTH
Revenue CAGR (5Y)	2.92%	32.84%
FCF CAGR (5Y)	-0.49%	59.88%
Total return CAGR (5Y)	30.72%	31.73%

Frequently asked

Which has the lower trailing P/E, LGND or LNTH?: LNTH has the lower trailing P/E: LGND trades at 31.72 and LNTH at 24.14. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, LGND or LNTH?: Over the past five years, LNTH grew revenue faster — LGND at a 2.92% CAGR versus LNTH at 32.84%.
Is LGND or LNTH more profitable?: LGND runs the higher net margin — LGND at 67.88% versus LNTH at 17.69%.
How have LGND and LNTH total returns compared?: Over the past 10 years, LGND delivered 17.12% and LNTH delivered 28.40% annualized total return. Past performance doesn't predict future results.

Go deeper

Full LGND analysis Full LNTH analysis Interactive comparison tool

Dig into the metrics

Ligand Pharmaceuticals P/E ratio Lantheus P/E ratio Ligand Pharmaceuticals ROE Lantheus ROE Ligand Pharmaceuticals operating margin Lantheus operating margin Ligand Pharmaceuticals revenue growth Lantheus revenue growth Ligand Pharmaceuticals free cash flow Lantheus free cash flow

Ligand Pharmaceuticals & Lantheus appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.