How have LENZ and SEER total returns compared?

Over the past 5 years, LENZ delivered -35.49% and SEER delivered -40.97% annualized total return. Past performance doesn't predict future results.

LENZ Therapeutics, Inc. (LENZ) vs Seer, Inc. (SEER)

A side-by-side comparison of LENZ Therapeutics, Inc. and Seer, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

LENZ

LENZ Therapeutics, Inc.

$119M

$3.79HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

SEER

Seer, Inc.

$120M

$2.19HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — LENZ vs SEER

growth of $100 · dividends reinvested · last 5y

LENZ -91.4% (-38.7%/yr)SEER -93.1% (-41.4%/yr)LENZ compounded faster over this window

LENZ SEER

LENZ vs SEER: by the numbers

•SEER is the larger company ($120M vs $119M market cap).
•Both run net losses; SEER's is the smaller (-490.71% vs -586.74% net margin).

Metrics side by side

Valuation

Metric	LENZ	SEER
P/S ratio	5.53	8.69
P/B ratio	0.54	0.53

Profitability

Metric	LENZ	SEER
Gross margin	90.14%	46.31%
Operating margin	-477.46%	-483.85%
Net margin	-586.74%	-490.71%
ROE	-57.47%	-30.12%
ROIC	-61.84%	-28.87%

Growth (annualized)

Metric	LENZ	SEER
Revenue CAGR (5Y)	N/A	51.57%
Total return CAGR (5Y)	-35.49%	-40.97%

Frequently asked

How have LENZ and SEER total returns compared?: Over the past 5 years, LENZ delivered -35.49% and SEER delivered -40.97% annualized total return. Past performance doesn't predict future results.

Go deeper

Full LENZ analysis Full SEER analysis Interactive comparison tool

Dig into the metrics

LENZ Therapeutics ROE Seer ROE LENZ Therapeutics operating margin Seer operating margin LENZ Therapeutics revenue growth Seer revenue growth LENZ Therapeutics free cash flow Seer free cash flow

LENZ Therapeutics & Seer appear in these rankings

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Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.