Which has the lower trailing P/E, KNSA or LNTH?

LNTH has the lower trailing P/E: KNSA trades at 76.88 and LNTH at 24.13. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, KNSA or LNTH?

Over the past five years, KNSA grew revenue faster — KNSA at a 155.66% CAGR versus LNTH at 32.84%.

Is KNSA or LNTH more profitable?

LNTH runs the higher net margin — KNSA at 9.59% versus LNTH at 17.69%.

How have KNSA and LNTH total returns compared?

Over the past 5 years, KNSA delivered 47.48% and LNTH delivered 31.73% annualized total return. Past performance doesn't predict future results.

Kiniksa Pharmaceuticals International, plc (KNSA) vs Lantheus Holdings, Inc. (LNTH)

A side-by-side comparison of Kiniksa Pharmaceuticals International, plc and Lantheus Holdings, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

KNSA

Kiniksa Pharmaceuticals International, plc

$5.74B

$75.34HealthcareDelayed quote: Oct 6, 2026, 1:20 PM EDT

LNTH

Lantheus Holdings, Inc.

$6.50B

$99.90HealthcareDelayed quote: Oct 6, 2026, 1:15 PM EDT

Total return — KNSA vs LNTH

growth of $100 · dividends reinvested · last 8y

KNSA +291.9% (+18.6%/yr)LNTH +623.4% (+28.1%/yr)LNTH compounded faster over this window

KNSA LNTH

KNSA vs LNTH: by the numbers

•LNTH is the larger company ($6.50B vs $5.74B market cap).
•LNTH trades at the lower trailing earnings multiple (24.13 vs 76.88 P/E), one valuation lens rather than an overall verdict.
•LNTH converts more revenue to profit (17.69% vs 9.59% net margin).
•KNSA grew revenue faster over the past five years (155.66% vs 32.84% CAGR).

Metrics side by side

Valuation

Metric	KNSA	LNTH
P/E ratio	76.88	24.13
Forward P/E	54.09	18.45
P/S ratio	6.83	4.18
P/B ratio	8.78	4.96
EV / EBITDA	54.63	16.98
FCF yield	3.19%	5.96%

Profitability

Metric	KNSA	LNTH
Gross margin	54.49%	60.14%
Operating margin	11.92%	19.43%
Net margin	9.59%	17.69%
ROE	12.33%	20.99%
ROIC	9.76%	11.03%

Growth (annualized)

Metric	KNSA	LNTH
Revenue CAGR (5Y)	155.66%	32.84%
FCF CAGR (5Y)	N/A	59.88%
Total return CAGR (5Y)	47.48%	31.73%

Frequently asked

Which has the lower trailing P/E, KNSA or LNTH?: LNTH has the lower trailing P/E: KNSA trades at 76.88 and LNTH at 24.13. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, KNSA or LNTH?: Over the past five years, KNSA grew revenue faster — KNSA at a 155.66% CAGR versus LNTH at 32.84%.
Is KNSA or LNTH more profitable?: LNTH runs the higher net margin — KNSA at 9.59% versus LNTH at 17.69%.
How have KNSA and LNTH total returns compared?: Over the past 5 years, KNSA delivered 47.48% and LNTH delivered 31.73% annualized total return. Past performance doesn't predict future results.

Go deeper

Full KNSA analysis Full LNTH analysis Interactive comparison tool

Dig into the metrics

Kiniksa Pharmaceuticals International P/E ratio Lantheus P/E ratio Kiniksa Pharmaceuticals International ROE Lantheus ROE Kiniksa Pharmaceuticals International operating margin Lantheus operating margin Kiniksa Pharmaceuticals International revenue growth Lantheus revenue growth Kiniksa Pharmaceuticals International free cash flow Lantheus free cash flow

Kiniksa Pharmaceuticals International & Lantheus appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.