Janux Therapeutics, Inc. (JANX) vs MeiraGTx Holdings plc (MGTX)

A side-by-side comparison of Janux Therapeutics, Inc. and MeiraGTx Holdings plc across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — JANX vs MGTX

growth of $100 · dividends reinvested · last 5y
JANX -34.2% (-8.0%/yr)MGTX -26.6% (-6.0%/yr)MGTX compounded faster over this window
100200Start $10020222023202420252026$66$73
JANX MGTX

JANX vs MGTX: by the numbers

  • •JANX is the larger company ($998M vs $985M market cap).
  • •MGTX is profitable (19.87% net margin) while JANX runs a net loss (-321.81%).
  • •JANX grew revenue faster over the past five years (105.89% vs 84.52% CAGR).

Metrics side by side

Valuation

MetricJANXMGTX
P/E ratioN/A14.99
Forward P/EN/A35.47
P/S ratio31.322.48
P/B ratio1.084.57
EV / EBITDAN/A4.86

Profitability

MetricJANXMGTX
Gross margin79.71%97.19%
Operating margin-1576.67%-130.20%
Net margin-321.81%19.87%
ROE-11.06%36.64%
ROIC-15.15%52.81%

Growth (annualized)

MetricJANXMGTX
Revenue CAGR (5Y)105.89%84.52%
Total return CAGR (5Y)-6.45%-3.10%

Some values include inputs from SEC filing.

Frequently asked

Which has grown faster, JANX or MGTX?
Over the past five years, JANX grew revenue faster — JANX at a 105.89% CAGR versus MGTX at 84.52%.
Is JANX or MGTX more profitable?
MGTX runs the higher net margin — JANX at -321.81% versus MGTX at 19.87%.
How have JANX and MGTX total returns compared?
Over the past 5 years, JANX delivered -6.45% and MGTX delivered -3.10% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.