Which has the lower trailing P/E, ISRG or TMO?

TMO has the lower trailing P/E: ISRG trades at 45.25 and TMO at 33.00. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, ISRG or TMO?

Over the past five years, ISRG grew revenue faster — ISRG at a 16.41% CAGR versus TMO at 5.00%.

Does ISRG or TMO pay a bigger dividend?

TMO pays a dividend (0.29% yield), while ISRG has no payments in the available dividend history.

Is ISRG or TMO more profitable?

ISRG runs the higher net margin — ISRG at 28.45% versus TMO at 15.06%.

How have ISRG and TMO total returns compared?

Over the past 10 years, ISRG delivered 17.94% and TMO delivered 15.19% annualized total return. Past performance doesn't predict future results.

Intuitive Surgical, Inc. (ISRG) vs Thermo Fisher Scientific Inc. (TMO)

A side-by-side comparison of Intuitive Surgical, Inc. and Thermo Fisher Scientific Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 20, 2026. Differences are shown without an overall score or investment verdict.

ISRG

Intuitive Surgical, Inc.

$140.51B

$397.72HealthcareAt close: Aug 19, 2026, 4:00 PM ET

TMO

Thermo Fisher Scientific Inc.

$228.00B

$613.54HealthcareAt close: Aug 19, 2026, 4:00 PM ET

Total return — ISRG vs TMO

growth of $100 · dividends reinvested · last 10y

ISRG +422.4% (+18.0%/yr)TMO +314.4% (+15.3%/yr)ISRG compounded faster over this window

ISRG TMO

ISRG vs TMO: by the numbers

•TMO is the larger company ($228.00B vs $140.51B market cap).
•TMO trades at the lower trailing earnings multiple (33.00 vs 45.25 P/E), one valuation lens rather than an overall verdict.
•ISRG converts more revenue to profit (28.45% vs 15.06% net margin).
•ISRG grew revenue faster over the past five years (16.41% vs 5.00% CAGR).
•TMO pays a dividend (0.29% yield), while ISRG has no payments in the available dividend history.

Metrics side by side

Valuation

Metric	ISRG	TMO
P/E ratio	45.25	33.00
Forward P/E	36.83	24.46
P/S ratio	12.92	4.91
P/B ratio	7.85	4.32
EV / EBITDA	33.04	25.34
FCF yield	2.26%	3.22%

Profitability

Metric	ISRG	TMO
Gross margin	66.68%	40.37%
Operating margin	31.28%	17.69%
Net margin	28.45%	15.06%
ROE	17.28%	13.25%
ROIC	15.11%	7.44%

Dividends

Metric	ISRG	TMO
Dividend yield	N/A	0.29%
Payout ratio	N/A	10.13%

Growth (annualized)

Metric	ISRG	TMO
Revenue CAGR (5Y)	16.41%	5.00%
EPS CAGR (5Y)	21.51%	1.99%
FCF CAGR (5Y)	14.17%	-1.83%
Total return CAGR (5Y)	2.48%	2.43%

Frequently asked

Which has the lower trailing P/E, ISRG or TMO?: TMO has the lower trailing P/E: ISRG trades at 45.25 and TMO at 33.00. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ISRG or TMO?: Over the past five years, ISRG grew revenue faster — ISRG at a 16.41% CAGR versus TMO at 5.00%.
Does ISRG or TMO pay a bigger dividend?: TMO pays a dividend (0.29% yield), while ISRG has no payments in the available dividend history.
Is ISRG or TMO more profitable?: ISRG runs the higher net margin — ISRG at 28.45% versus TMO at 15.06%.
How have ISRG and TMO total returns compared?: Over the past 10 years, ISRG delivered 17.94% and TMO delivered 15.19% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ISRG analysis Full TMO analysis Interactive comparison tool

Dig into the metrics

Intuitive Surgical P/E ratio Thermo Fisher Scientific P/E ratio Thermo Fisher Scientific dividend yield Intuitive Surgical ROE Thermo Fisher Scientific ROE Intuitive Surgical operating margin Thermo Fisher Scientific operating margin Intuitive Surgical revenue growth Thermo Fisher Scientific revenue growth Intuitive Surgical free cash flow Thermo Fisher Scientific free cash flow

Intuitive Surgical & Thermo Fisher Scientific appear in these rankings

Fastest Revenue Growth Stocks Highest Operating Margin Stocks Highest 10-Year Total Return Stocks Largest Companies by Market Cap

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 20, 2026.