Is ISRG or TMO cheaper?

On trailing earnings, TMO is cheaper: ISRG trades at a 49.83 P/E and TMO at 25.80.

Which has grown faster, ISRG or TMO?

Over the past five years, ISRG grew revenue faster — ISRG at a 18.39% CAGR versus TMO at 6.68%.

Does ISRG or TMO pay a bigger dividend?

TMO pays a dividend (0.38% yield) while ISRG does not currently pay one.

Is ISRG or TMO more profitable?

ISRG runs the higher net margin — ISRG at 28.15% versus TMO at 15.18%.

Which has been the better investment, ISRG or TMO?

Over the past 10-year, ISRG delivered the higher annualized total return — ISRG at 19.14% versus TMO at 12.26%. Past performance doesn't predict future results.

Intuitive Surgical, Inc. (ISRG) vs Thermo Fisher Scientific Inc. (TMO)

ISRG leads on 10 of 16 compared metrics, though TMO is the cheaper stock.

A side-by-side comparison of Intuitive Surgical, Inc. and Thermo Fisher Scientific Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 15, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

ISRG

Intuitive Surgical, Inc.

$145.58B

$411.06Healthcare

TMO

Thermo Fisher Scientific Inc.

$174.42B

$469.34Healthcare

Total return — ISRG vs TMO

growth of $100 · last 26y

ISRG +20149.3%TMO +2922.2%ISRG compounded faster

Log scale — wide-divergence pair

ISRG TMO

ISRG vs TMO: by the numbers

•TMO is the larger company ($174.42B vs $145.58B market cap).
•TMO trades at the lower earnings multiple (25.80 vs 49.83 P/E).
•ISRG converts more revenue to profit (28.15% vs 15.18% net margin).
•ISRG grew revenue faster over the past five years (18.39% vs 6.68% CAGR).
•TMO pays a dividend (0.38% yield) while ISRG does not currently pay one.

Which is better, ISRG or TMO?

Metric tally: ISRG 10 · TMO 6

It depends on what you're optimizing for:

ValueTMO(lower P/E)

GrowthISRG(faster 5Y revenue CAGR)

QualityISRG(higher ROIC)

Metrics side by side

Valuation

Metric	ISRG	TMO
P/E ratio	49.83	25.80●
Forward P/E	34.92	17.26●
P/S ratio	13.98	3.87●
P/B ratio	8.46	3.37●
PEG ratio	3.17●	4.51
EV / EBITDA	35.41	19.26●
FCF yield	1.92%	3.86%●

Profitability

Metric	ISRG	TMO
Gross margin	66.29%●	39.41%
Operating margin	30.45%●	17.76%
Net margin	28.15%●	15.18%
ROE	17.05%●	13.21%
ROIC	13.71%●	7.58%

Dividends

Metric	ISRG	TMO
Dividend yield	—	0.38%
Payout ratio	—	10.13%

Growth (annualized)

Metric	ISRG	TMO
Revenue CAGR (5Y)	18.39%●	6.68%
EPS CAGR (5Y)	21.51%●	1.99%
FCF CAGR (5Y)	16.61%●	-0.19%
Total return CAGR (5Y)	7.37%●	0.45%

Frequently asked

Which is better, ISRG or TMO?: It depends on your goal. value: TMO (lower P/E); growth: ISRG (faster 5Y revenue CAGR); quality: ISRG (higher ROIC). Across all compared metrics, ISRG leads 10 to 6.
Is ISRG or TMO cheaper?: On trailing earnings, TMO is cheaper: ISRG trades at a 49.83 P/E and TMO at 25.80.
Which has grown faster, ISRG or TMO?: Over the past five years, ISRG grew revenue faster — ISRG at a 18.39% CAGR versus TMO at 6.68%.
Does ISRG or TMO pay a bigger dividend?: TMO pays a dividend (0.38% yield) while ISRG does not currently pay one.
Is ISRG or TMO more profitable?: ISRG runs the higher net margin — ISRG at 28.15% versus TMO at 15.18%.
Which has been the better investment, ISRG or TMO?: Over the past 10-year, ISRG delivered the higher annualized total return — ISRG at 19.14% versus TMO at 12.26%. Past performance doesn't predict future results.

Go deeper

Full ISRG analysis Full TMO analysis Interactive comparison tool

Dig into the metrics

Intuitive Surgical P/E ratio Thermo Fisher Scientific P/E ratio Intuitive Surgical dividend yield Thermo Fisher Scientific dividend yield Intuitive Surgical ROE Thermo Fisher Scientific ROE Intuitive Surgical operating margin Thermo Fisher Scientific operating margin Intuitive Surgical revenue growth Thermo Fisher Scientific revenue growth Intuitive Surgical free cash flow Thermo Fisher Scientific free cash flow

Intuitive Surgical & Thermo Fisher Scientific appear in these rankings

Fastest Revenue Growth Stocks Highest Operating Margin Stocks Best 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 15, 2026.