Which has the lower trailing P/E, ISRG or SYK?

SYK has the lower trailing P/E: ISRG trades at 40.20 and SYK at 33.75. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, ISRG or SYK?

Over the past five years, ISRG grew revenue faster — ISRG at a 16.41% CAGR versus SYK at 9.72%.

Does ISRG or SYK pay a bigger dividend?

SYK pays a dividend (1.07% yield), while ISRG has no payments in the available dividend history.

Is ISRG or SYK more profitable?

ISRG runs the higher net margin — ISRG at 28.45% versus SYK at 14.43%.

How have ISRG and SYK total returns compared?

Over the past 10 years, ISRG delivered 16.40% and SYK delivered 12.07% annualized total return. Past performance doesn't predict future results.

Intuitive Surgical, Inc. (ISRG) vs Stryker Corporation (SYK)

A side-by-side comparison of Intuitive Surgical, Inc. and Stryker Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 1, 2026. Differences are shown without an overall score or investment verdict.

ISRG

Intuitive Surgical, Inc.

$124.82B

$353.33HealthcareAt close: Jul 31, 2026, 4:00 PM ET

SYK

Stryker Corporation

$124.86B

$325.70HealthcareAt close: Jul 31, 2026, 4:00 PM ET

Total return — ISRG vs SYK

growth of $100 · dividends reinvested · last 26y

ISRG +17305.4%SYK +2178.8%ISRG compounded faster

Log scale — wide-divergence pair

ISRG SYK

ISRG vs SYK: by the numbers

•SYK is the larger company ($124.86B vs $124.82B market cap).
•SYK trades at the lower trailing earnings multiple (33.75 vs 40.20 P/E), one valuation lens rather than an overall verdict.
•ISRG converts more revenue to profit (28.45% vs 14.43% net margin).
•ISRG grew revenue faster over the past five years (16.41% vs 9.72% CAGR).
•SYK pays a dividend (1.07% yield), while ISRG has no payments in the available dividend history.

Metrics side by side

Valuation

Metric	ISRG	SYK
P/E ratio	40.20	33.75
Forward P/E	32.72	21.73
P/S ratio	11.48	4.87
P/B ratio	6.97	2.62
PEG ratio	3.17	5.16
EV / EBITDA	29.28	20.56
FCF yield	2.54%	3.63%

Profitability

Metric	ISRG	SYK
Gross margin	66.68%	65.17%
Operating margin	31.28%	22.03%
Net margin	28.45%	14.43%
ROE	17.28%	7.78%
ROIC	13.71%	8.53%

Dividends

Metric	ISRG	SYK
Dividend yield	N/A	1.07%
Payout ratio	N/A	40.99%

Growth (annualized)

Metric	ISRG	SYK
Revenue CAGR (5Y)	16.41%	9.72%
EPS CAGR (5Y)	21.51%	14.79%
FCF CAGR (5Y)	14.17%	11.01%
Total return CAGR (5Y)	1.34%	4.83%

Frequently asked

Which has the lower trailing P/E, ISRG or SYK?: SYK has the lower trailing P/E: ISRG trades at 40.20 and SYK at 33.75. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ISRG or SYK?: Over the past five years, ISRG grew revenue faster — ISRG at a 16.41% CAGR versus SYK at 9.72%.
Does ISRG or SYK pay a bigger dividend?: SYK pays a dividend (1.07% yield), while ISRG has no payments in the available dividend history.
Is ISRG or SYK more profitable?: ISRG runs the higher net margin — ISRG at 28.45% versus SYK at 14.43%.
How have ISRG and SYK total returns compared?: Over the past 10 years, ISRG delivered 16.40% and SYK delivered 12.07% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ISRG analysis Full SYK analysis Interactive comparison tool

Dig into the metrics

Intuitive Surgical P/E ratio Stryker P/E ratio Intuitive Surgical dividend yield Stryker dividend yield Intuitive Surgical ROE Stryker ROE Intuitive Surgical operating margin Stryker operating margin Intuitive Surgical revenue growth Stryker revenue growth Intuitive Surgical free cash flow Stryker free cash flow

Intuitive Surgical & Stryker appear in these rankings

25+ Year Dividend Growers Fastest Revenue Growth Stocks Highest Operating Margin Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 1, 2026.