Which has the lower trailing P/E, ISRG or SYK?

SYK has the lower trailing P/E: ISRG trades at 43.38 and SYK at 29.55. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, ISRG or SYK?

Over the past five years, ISRG grew revenue faster — ISRG at a 16.41% CAGR versus SYK at 9.72%.

Does ISRG or SYK pay a bigger dividend?

SYK pays a dividend (1.26% yield), while ISRG has no payments in the available dividend history.

Is ISRG or SYK more profitable?

ISRG runs the higher net margin — ISRG at 28.45% versus SYK at 14.43%.

How have ISRG and SYK total returns compared?

Over the past 10 years, ISRG delivered 17.25% and SYK delivered 10.77% annualized total return. Past performance doesn't predict future results.

Intuitive Surgical, Inc. (ISRG) vs Stryker Corporation (SYK)

A side-by-side comparison of Intuitive Surgical, Inc. and Stryker Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 13, 2026. Differences are shown without an overall score or investment verdict.

ISRG

Intuitive Surgical, Inc.

$134.71B

$381.32HealthcareDelayed quote: Sep 16, 2026, 9:55 AM EDT

SYK

Stryker Corporation

$109.32B

$285.17HealthcareDelayed quote: Sep 16, 2026, 9:55 AM EDT

Total return — ISRG vs SYK

growth of $100 · dividends reinvested · last 10y

ISRG +384.1% (+17.1%/yr)SYK +169.1% (+10.4%/yr)ISRG compounded faster over this window

ISRG SYK

ISRG vs SYK: by the numbers

•ISRG is the larger company ($134.71B vs $109.32B market cap).
•SYK trades at the lower trailing earnings multiple (29.55 vs 43.38 P/E), one valuation lens rather than an overall verdict.
•ISRG converts more revenue to profit (28.45% vs 14.43% net margin).
•ISRG grew revenue faster over the past five years (16.41% vs 9.72% CAGR).
•SYK pays a dividend (1.26% yield), while ISRG has no payments in the available dividend history.

Metrics side by side

Valuation

Metric	ISRG	SYK
P/E ratio	43.38	29.55
Forward P/E	35.31	19.00
P/S ratio	12.21	4.23
P/B ratio	7.41	4.56
EV / EBITDA	31.18	17.42
FCF yield	2.39%	4.30%

Profitability

Metric	ISRG	SYK
Gross margin	66.68%	65.17%
Operating margin	31.28%	22.03%
Net margin	28.45%	14.43%
ROE	17.28%	15.55%
ROIC	15.11%	9.82%

Dividends

Metric	ISRG	SYK
Dividend yield	N/A	1.26%
Payout ratio	N/A	36.06%

Growth (annualized)

Metric	ISRG	SYK
Revenue CAGR (5Y)	16.41%	9.72%
EPS CAGR (5Y)	21.51%	14.79%
FCF CAGR (5Y)	14.17%	9.60%
Total return CAGR (5Y)	1.59%	1.16%

Frequently asked

Which has the lower trailing P/E, ISRG or SYK?: SYK has the lower trailing P/E: ISRG trades at 43.38 and SYK at 29.55. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ISRG or SYK?: Over the past five years, ISRG grew revenue faster — ISRG at a 16.41% CAGR versus SYK at 9.72%.
Does ISRG or SYK pay a bigger dividend?: SYK pays a dividend (1.26% yield), while ISRG has no payments in the available dividend history.
Is ISRG or SYK more profitable?: ISRG runs the higher net margin — ISRG at 28.45% versus SYK at 14.43%.
How have ISRG and SYK total returns compared?: Over the past 10 years, ISRG delivered 17.25% and SYK delivered 10.77% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ISRG analysis Full SYK analysis Interactive comparison tool

Dig into the metrics

Intuitive Surgical P/E ratio Stryker P/E ratio Stryker dividend yield Intuitive Surgical ROE Stryker ROE Intuitive Surgical operating margin Stryker operating margin Intuitive Surgical revenue growth Stryker revenue growth Intuitive Surgical free cash flow Stryker free cash flow

Intuitive Surgical & Stryker appear in these rankings

Fastest Revenue Growth Stocks Highest Operating Margin Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 13, 2026.