Intuitive Surgical, Inc. (ISRG) vs Sanofi (SNY)
A side-by-side comparison of Intuitive Surgical, Inc. and Sanofi across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 28, 2026. Differences are shown without an overall score or investment verdict.
ISRG
Intuitive Surgical, Inc.
$371.47HealthcareDelayed quote: Aug 28, 2026, 12:20 PM EDT
SNY
Sanofi
$44.73HealthcareDelayed quote: Aug 28, 2026, 12:20 PM EDT
Total return — ISRG vs SNY
growth of $100 · dividends reinvested · last 10yISRG +382.1% (+17.0%/yr)SNY +72.2% (+5.6%/yr)ISRG compounded faster over this window
ISRG SNY
ISRG vs SNY: by the numbers
- •ISRG is the larger company ($131.23B vs $107.40B market cap).
- •ISRG trades at the lower trailing earnings multiple (41.76 vs 80.55 P/E), one valuation lens rather than an overall verdict.
- •ISRG converts more revenue to profit (28.45% vs 8.10% net margin).
- •ISRG grew revenue faster over the past five years (16.41% vs 4.96% CAGR).
- •SNY pays a dividend (5.39% yield), while ISRG has no payments in the available dividend history.
Metrics side by side
Valuation
| Metric | ISRG | SNY |
|---|---|---|
| P/E ratio | 41.76 | 80.55 |
| Forward P/E | 33.99 | N/A |
| P/S ratio | 11.93 | 1.89 |
| P/B ratio | 7.24 | 1.36 |
| EV / EBITDA | 30.44 | 10.17 |
| FCF yield | 2.45% | 12.72% |
Profitability
| Metric | ISRG | SNY |
|---|---|---|
| Gross margin | 66.68% | 73.01% |
| Operating margin | 31.28% | 14.74% |
| Net margin | 28.45% | 8.10% |
| ROE | 17.28% | 5.82% |
| ROIC | 15.11% | 5.42% |
Dividends
| Metric | ISRG | SNY |
|---|---|---|
| Dividend yield | N/A | 5.39% |
| Payout ratio | N/A | 64.36% |
Growth (annualized)
| Metric | ISRG | SNY |
|---|---|---|
| Revenue CAGR (5Y) | 16.41% | 4.96% |
| EPS CAGR (5Y) | 21.51% | -8.92% |
| FCF CAGR (5Y) | 14.17% | 12.83% |
| Total return CAGR (5Y) | 1.22% | 1.38% |
Frequently asked
- Which has the lower trailing P/E, ISRG or SNY?
- ISRG has the lower trailing P/E: ISRG trades at 41.76 and SNY at 80.55. P/E is one valuation measure and does not by itself establish which business is cheaper.
- Which has grown faster, ISRG or SNY?
- Over the past five years, ISRG grew revenue faster — ISRG at a 16.41% CAGR versus SNY at 4.96%.
- Does ISRG or SNY pay a bigger dividend?
- SNY pays a dividend (5.39% yield), while ISRG has no payments in the available dividend history.
- Is ISRG or SNY more profitable?
- ISRG runs the higher net margin — ISRG at 28.45% versus SNY at 8.10%.
- How have ISRG and SNY total returns compared?
- Over the past 10 years, ISRG delivered 17.03% and SNY delivered 5.69% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Intuitive Surgical P/E ratioSanofi P/E ratioSanofi dividend yieldIntuitive Surgical ROESanofi ROEIntuitive Surgical operating marginSanofi operating marginIntuitive Surgical revenue growthSanofi revenue growthIntuitive Surgical free cash flowSanofi free cash flow
Intuitive Surgical & Sanofi appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 28, 2026.