Intuitive Surgical, Inc. (ISRG) vs Novo Nordisk A/S (NVO)
A side-by-side comparison of Intuitive Surgical, Inc. and Novo Nordisk A/S across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 5, 2026. Differences are shown without an overall score or investment verdict.
ISRG
Intuitive Surgical, Inc.
$370.52HealthcareDelayed quote: Aug 5, 2026, 11:40 AM EDT
NVO
Novo Nordisk A/S
$45.05HealthcareDelayed quote: Aug 5, 2026, 11:40 AM EDT
Total return — ISRG vs NVO
growth of $100 · dividends reinvested · last 26yISRG +18041.4%NVO +4169.3%ISRG compounded faster
ISRG NVO
ISRG vs NVO: by the numbers
- •NVO is the larger company ($200.17B vs $130.89B market cap).
- •NVO trades at the lower trailing earnings multiple (10.36 vs 41.90 P/E), one valuation lens rather than an overall verdict.
- •NVO converts more revenue to profit (37.14% vs 28.45% net margin).
- •NVO grew revenue faster over the past five years (20.73% vs 16.41% CAGR).
- •NVO pays a dividend (4.07% yield), while ISRG has no payments in the available dividend history.
Metrics side by side
Valuation
| Metric | ISRG | NVO |
|---|---|---|
| P/E ratio | 41.90 | 10.36 |
| Forward P/E | 34.10 | N/A |
| P/S ratio | 11.96 | 3.85 |
| P/B ratio | 7.27 | 6.29 |
| PEG ratio | 3.17 | 8.16 |
| EV / EBITDA | 30.54 | 8.15 |
| FCF yield | 2.44% | 2.46% |
Profitability
| Metric | ISRG | NVO |
|---|---|---|
| Gross margin | 66.68% | 81.83% |
| Operating margin | 31.28% | 45.21% |
| Net margin | 28.45% | 37.14% |
| ROE | 17.28% | 60.74% |
| ROIC | 13.71% | 29.53% |
Dividends
| Metric | ISRG | NVO |
|---|---|---|
| Dividend yield | N/A | 4.07% |
| Payout ratio | N/A | 49.80% |
Growth (annualized)
| Metric | ISRG | NVO |
|---|---|---|
| Revenue CAGR (5Y) | 16.41% | 20.73% |
| EPS CAGR (5Y) | 21.51% | 19.59% |
| FCF CAGR (5Y) | 14.17% | -5.86% |
| Total return CAGR (5Y) | 2.20% | 0.02% |
Frequently asked
- Which has the lower trailing P/E, ISRG or NVO?
- NVO has the lower trailing P/E: ISRG trades at 41.90 and NVO at 10.36. P/E is one valuation measure and does not by itself establish which business is cheaper.
- Which has grown faster, ISRG or NVO?
- Over the past five years, NVO grew revenue faster — ISRG at a 16.41% CAGR versus NVO at 20.73%.
- Does ISRG or NVO pay a bigger dividend?
- NVO pays a dividend (4.07% yield), while ISRG has no payments in the available dividend history.
- Is ISRG or NVO more profitable?
- NVO runs the higher net margin — ISRG at 28.45% versus NVO at 37.14%.
- How have ISRG and NVO total returns compared?
- Over the past 10 years, ISRG delivered 16.93% and NVO delivered 7.28% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Intuitive Surgical P/E ratioNovo Nordisk A/S P/E ratioIntuitive Surgical dividend yieldNovo Nordisk A/S dividend yieldIntuitive Surgical ROENovo Nordisk A/S ROEIntuitive Surgical operating marginNovo Nordisk A/S operating marginIntuitive Surgical revenue growthNovo Nordisk A/S revenue growthIntuitive Surgical free cash flowNovo Nordisk A/S free cash flow
Intuitive Surgical & Novo Nordisk A/S appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 5, 2026.