Is ISRG or MCK cheaper?

On trailing earnings, MCK is cheaper: ISRG trades at a 40.18 P/E and MCK at 21.61.

Which has grown faster, ISRG or MCK?

Over the past five years, ISRG grew revenue faster — ISRG at a 16.41% CAGR versus MCK at 11.11%.

Does ISRG or MCK pay a bigger dividend?

MCK pays a dividend (0.39% yield) while ISRG does not currently pay one.

Is ISRG or MCK more profitable?

ISRG runs the higher net margin — ISRG at 28.45% versus MCK at 1.18%.

Intuitive Surgical, Inc. (ISRG) vs McKesson Corporation (MCK)

MCK leads on 9 of 15 compared metrics.

A side-by-side comparison of Intuitive Surgical, Inc. and McKesson Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 20, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

ISRG

Intuitive Surgical, Inc.

$125.08B

$353.17HealthcareDelayed quote: Jul 20, 2026, 4:00 PM EDT

MCK

McKesson Corporation

$97.35B

$831.46HealthcareDelayed quote: Jul 20, 2026, 4:00 PM EDT

Total return — ISRG vs MCK

growth of $100 · dividends reinvested · last 26y

ISRG +17297.5%MCK +4898.4%ISRG compounded faster

ISRG MCK

ISRG vs MCK: by the numbers

•ISRG is the larger company ($125.08B vs $97.35B market cap).
•MCK trades at the lower earnings multiple (21.61 vs 40.18 P/E).
•ISRG converts more revenue to profit (28.45% vs 1.18% net margin).
•ISRG grew revenue faster over the past five years (16.41% vs 11.11% CAGR).
•MCK pays a dividend (0.39% yield) while ISRG does not currently pay one.

Which is better, ISRG or MCK?

Metric tally: ISRG 6 · MCK 9

It depends on what you're optimizing for:

ValueMCK(lower P/E)

GrowthISRG(faster 5Y revenue CAGR)

QualityMCK(higher ROIC)

Metrics side by side

Valuation

Metric	ISRG	MCK
P/E ratio	40.18	21.61●
Forward P/E	32.96	21.31●
P/S ratio	11.47	0.25●
P/B ratio	6.92	—
PEG ratio	3.17	0.46●
EV / EBITDA	27.88	15.02●
FCF yield	2.23%	5.82%●

Profitability

Metric	ISRG	MCK
Gross margin	66.68%●	3.61%
Operating margin	31.28%●	1.58%
Net margin	28.45%●	1.18%
ROE	17.15%●	-219.24%
ROIC	13.71%	31.48%●

Dividends

Metric	ISRG	MCK
Dividend yield	—	0.39%
Payout ratio	—	8.51%

Growth (annualized)

Metric	ISRG	MCK
Revenue CAGR (5Y)	16.41%●	11.11%
EPS CAGR (5Y)	21.51%	40.71%●
FCF CAGR (5Y)	16.61%●	8.76%
Total return CAGR (5Y)	2.10%	34.47%●

Frequently asked

Which is better, ISRG or MCK?: It depends on your goal. value: MCK (lower P/E); growth: ISRG (faster 5Y revenue CAGR); quality: MCK (higher ROIC). Across all compared metrics, MCK leads 9 to 6.
Is ISRG or MCK cheaper?: On trailing earnings, MCK is cheaper: ISRG trades at a 40.18 P/E and MCK at 21.61.
Which has grown faster, ISRG or MCK?: Over the past five years, ISRG grew revenue faster — ISRG at a 16.41% CAGR versus MCK at 11.11%.
Does ISRG or MCK pay a bigger dividend?: MCK pays a dividend (0.39% yield) while ISRG does not currently pay one.
Is ISRG or MCK more profitable?: ISRG runs the higher net margin — ISRG at 28.45% versus MCK at 1.18%.

Go deeper

Full ISRG analysis Full MCK analysis Interactive comparison tool

Dig into the metrics

Intuitive Surgical P/E ratio McKesson P/E ratio Intuitive Surgical dividend yield McKesson dividend yield Intuitive Surgical ROE McKesson ROE Intuitive Surgical operating margin McKesson operating margin Intuitive Surgical revenue growth McKesson revenue growth Intuitive Surgical free cash flow McKesson free cash flow

Intuitive Surgical & McKesson appear in these rankings

Fastest Revenue Growth Stocks Highest ROIC Stocks Highest Operating Margin Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 20, 2026.