Ironwood Pharmaceuticals, Inc. (IRWD) vs SOPHiA GENETICS S.A. (SOPH)
A side-by-side comparison of Ironwood Pharmaceuticals, Inc. and SOPHiA GENETICS S.A. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
IRWD
Ironwood Pharmaceuticals, Inc.
$3.66HealthcareDelayed quote: Oct 6, 2026, 3:00 PM EDT
SOPH
SOPHiA GENETICS S.A.
$7.43HealthcareDelayed quote: Oct 6, 2026, 3:00 PM EDT
Total return — IRWD vs SOPH
growth of $100 · dividends reinvested · last 5yIRWD -72.5% (-22.7%/yr)SOPH -51.1% (-13.3%/yr)SOPH compounded faster over this window
IRWD SOPH
IRWD vs SOPH: by the numbers
- •SOPH is the larger company ($623M vs $602M market cap).
- •IRWD is profitable (33.36% net margin) while SOPH runs a net loss (-93.86%).
- •SOPH grew revenue faster over the past five years (20.33% vs -1.18% CAGR).
Metrics side by side
Valuation
| Metric | IRWD | SOPH |
|---|---|---|
| P/E ratio | 4.76 | N/A |
| Forward P/E | 2.99 | N/A |
| P/S ratio | 1.55 | 7.24 |
| P/B ratio | N/A | 7.50 |
| EV / EBITDA | 3.86 | N/A |
| FCF yield | 30.84% | N/A |
Profitability
| Metric | IRWD | SOPH |
|---|---|---|
| Gross margin | 99.76% | 66.63% |
| Operating margin | 40.10% | -85.01% |
| Net margin | 33.36% | -93.86% |
| ROE | N/A | -97.31% |
| ROIC | 58.60% | -49.73% |
Growth (annualized)
| Metric | IRWD | SOPH |
|---|---|---|
| Revenue CAGR (5Y) | -1.18% | 20.33% |
| EPS CAGR (5Y) | -25.87% | N/A |
| FCF CAGR (5Y) | -3.98% | N/A |
| Total return CAGR (5Y) | -22.82% | -13.62% |
Frequently asked
- Which has grown faster, IRWD or SOPH?
- Over the past five years, SOPH grew revenue faster — IRWD at a -1.18% CAGR versus SOPH at 20.33%.
- Is IRWD or SOPH more profitable?
- IRWD runs the higher net margin — IRWD at 33.36% versus SOPH at -93.86%.
- How have IRWD and SOPH total returns compared?
- Over the past 5 years, IRWD delivered -22.82% and SOPH delivered -13.62% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Ironwood Pharmaceuticals P/E ratioIronwood Pharmaceuticals ROESOPHiA GENETICS ROEIronwood Pharmaceuticals operating marginSOPHiA GENETICS operating marginIronwood Pharmaceuticals revenue growthSOPHiA GENETICS revenue growthIronwood Pharmaceuticals free cash flowSOPHiA GENETICS free cash flow
Ironwood Pharmaceuticals & SOPHiA GENETICS appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.