Opus Genetics, Inc. (IRD) vs Orchestra BioMed Holdings, Inc. (OBIO)
A side-by-side comparison of Opus Genetics, Inc. and Orchestra BioMed Holdings, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
IRD
Opus Genetics, Inc.
$4.35HealthcareDelayed quote: Oct 6, 2026, 1:30 PM EDT
OBIO
Orchestra BioMed Holdings, Inc.
$5.90HealthcareDelayed quote: Oct 6, 2026, 1:29 PM EDT
Total return — IRD vs OBIO
growth of $100 · dividends reinvested · last 2yIRD +239.5% (+84.3%/yr)OBIO +28.6% (+13.4%/yr)IRD compounded faster over this window
IRD OBIO
IRD vs OBIO: by the numbers
- •IRD is the larger company ($359M vs $353M market cap).
- •Both run net losses; OBIO's is the smaller (-184.60% vs -1091.82% net margin).
- •IRD grew revenue faster over the past five years (150.49% vs 148.45% CAGR).
Metrics side by side
Valuation
| Metric | IRD | OBIO |
|---|---|---|
| P/S ratio | 36.44 | 11.04 |
| P/B ratio | N/A | 18.27 |
Profitability
| Metric | IRD | OBIO |
|---|---|---|
| Gross margin | 99.87% | 99.32% |
| Operating margin | -271.90% | -154.73% |
| Net margin | -1091.82% | -184.60% |
| ROE | N/A | -200.64% |
| ROIC | -59.29% | -56.73% |
Growth (annualized)
| Metric | IRD | OBIO |
|---|---|---|
| Revenue CAGR (5Y) | 150.49% | 148.45% |
| Total return CAGR (5Y) | N/A | -9.35% |
Frequently asked
- Which has grown faster, IRD or OBIO?
- Over the past five years, IRD grew revenue faster — IRD at a 150.49% CAGR versus OBIO at 148.45%.
Go deeper
Dig into the metrics
Opus Genetics ROEOrchestra BioMed ROEOpus Genetics operating marginOrchestra BioMed operating marginOpus Genetics revenue growthOrchestra BioMed revenue growthOpus Genetics free cash flowOrchestra BioMed free cash flow
Opus Genetics & Orchestra BioMed appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.