Which has grown faster, INSP or URGN?

Over the past five years, URGN grew revenue faster — INSP at a 38.69% CAGR versus URGN at 42.66%.

Is INSP or URGN more profitable?

INSP runs the higher net margin — INSP at 15.03% versus URGN at -51.73%.

How have INSP and URGN total returns compared?

Over the past 5 years, INSP delivered -21.38% and URGN delivered 20.32% annualized total return. Past performance doesn't predict future results.

Inspire Medical Systems, Inc. (INSP) vs UroGen Pharma Ltd. (URGN)

A side-by-side comparison of Inspire Medical Systems, Inc. and UroGen Pharma Ltd. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

INSP

Inspire Medical Systems, Inc.

$1.97B

$68.20HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

URGN

UroGen Pharma Ltd.

$2.02B

$41.43HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — INSP vs URGN

growth of $100 · dividends reinvested · last 8y

INSP +183.2% (+13.9%/yr)URGN -25.3% (-3.6%/yr)INSP compounded faster over this window

INSP URGN

INSP vs URGN: by the numbers

•URGN is the larger company ($2.02B vs $1.97B market cap).
•INSP is profitable (15.03% net margin) while URGN runs a net loss (-51.73%).
•URGN grew revenue faster over the past five years (42.66% vs 38.69% CAGR).

Metrics side by side

Valuation

Metric	INSP	URGN
P/E ratio	14.76	N/A
Forward P/E	57.10	N/A
P/S ratio	2.19	10.70
P/B ratio	2.39	N/A
EV / EBITDA	26.26	N/A
FCF yield	5.94%	N/A

Profitability

Metric	INSP	URGN
Gross margin	86.13%	90.85%
Operating margin	6.02%	-113.73%
Net margin	15.03%	-51.73%
ROE	16.36%	N/A
ROIC	6.33%	-34.96%

Growth (annualized)

Metric	INSP	URGN
Revenue CAGR (5Y)	38.69%	42.66%
Total return CAGR (5Y)	-21.38%	20.32%

Frequently asked

Which has grown faster, INSP or URGN?: Over the past five years, URGN grew revenue faster — INSP at a 38.69% CAGR versus URGN at 42.66%.
Is INSP or URGN more profitable?: INSP runs the higher net margin — INSP at 15.03% versus URGN at -51.73%.
How have INSP and URGN total returns compared?: Over the past 5 years, INSP delivered -21.38% and URGN delivered 20.32% annualized total return. Past performance doesn't predict future results.

Go deeper

Full INSP analysis Full URGN analysis Interactive comparison tool

Dig into the metrics

Inspire Medical Systems P/E ratio Inspire Medical Systems ROE UroGen Pharma ROE Inspire Medical Systems operating margin UroGen Pharma operating margin Inspire Medical Systems revenue growth UroGen Pharma revenue growth Inspire Medical Systems free cash flow UroGen Pharma free cash flow

Inspire Medical Systems & UroGen Pharma appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks Lowest P/E Ratio Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.