Inovio Pharmaceuticals, Inc. (INO) vs Sera Prognostics, Inc. (SERA)

A side-by-side comparison of Inovio Pharmaceuticals, Inc. and Sera Prognostics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — INO vs SERA

growth of $100 · dividends reinvested · last 5y
INO -98.8% (-58.7%/yr)SERA -83.2% (-30.0%/yr)SERA compounded faster over this window
Log scale — wide-divergence pair
01101001kStart $10020222023202420252026$1$17
INO SERA

INO vs SERA: by the numbers

  • •INO is the larger company ($79M vs $77M market cap).
  • •Both run net losses; SERA's is the smaller (-47475.71% vs -130000.00% net margin).

Metrics side by side

Valuation

MetricINOSERA
P/S ratioN/A1102.08
P/B ratio18.131.30

Profitability

MetricINOSERA
Gross margin100.00%-102.47%
Operating margin-132871.32%-45066.67%
Net margin-130000.00%-47475.71%
ROE-1542.57%-55.97%
ROIC-836.58%-59.79%

Growth (annualized)

MetricINOSERA
Revenue CAGR (5Y)N/A9.73%
Total return CAGR (5Y)-57.05%-28.91%

Frequently asked

How have INO and SERA total returns compared?
Over the past 5 years, INO delivered -57.05% and SERA delivered -28.91% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.