Which has the lower trailing P/E, INCY or MDLN?

INCY has the lower trailing P/E: INCY trades at 16.37 and MDLN at 39.43. P/E is one valuation measure and does not by itself establish which business is cheaper.

Is INCY or MDLN more profitable?

INCY runs the higher net margin — INCY at 27.71% versus MDLN at 2.31%.

Incyte Corporation (INCY) vs Medline Inc. (MDLN)

A side-by-side comparison of Incyte Corporation and Medline Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 20, 2026. Differences are shown without an overall score or investment verdict.

INCY

Incyte Corporation

$26.04B

$128.47HealthcareAt close: Aug 19, 2026, 4:00 PM ET

MDLN

Medline Inc.

$28.67B

$33.91HealthcareAt close: Aug 19, 2026, 4:00 PM ET

Total return — INCY vs MDLN

growth of $100 · dividends reinvested · last 1y

INCY +33.7% (+33.7%/yr)MDLN -17.3% (-17.3%/yr)INCY compounded faster over this window

INCY MDLN

INCY vs MDLN: by the numbers

•MDLN is the larger company ($28.67B vs $26.04B market cap).
•INCY trades at the lower trailing earnings multiple (16.37 vs 39.43 P/E), one valuation lens rather than an overall verdict.
•INCY converts more revenue to profit (27.71% vs 2.31% net margin).

Metrics side by side

Valuation

Metric	INCY	MDLN
P/E ratio	16.37	39.43
Forward P/E	30.72	22.16
P/S ratio	4.60	0.98
P/B ratio	4.22	2.52
EV / EBITDA	11.78	14.34
FCF yield	7.18%	6.94%

Profitability

Metric	INCY	MDLN
Gross margin	92.62%	25.02%
Operating margin	31.57%	6.07%
Net margin	27.71%	2.31%
ROE	25.41%	5.97%
ROIC	22.95%	4.05%

Growth (annualized)

Metric	INCY	MDLN
Revenue CAGR (5Y)	16.43%	N/A
EPS CAGR (5Y)	21.19%	N/A
FCF CAGR (5Y)	33.69%	N/A
Total return CAGR (5Y)	11.51%	N/A

Frequently asked

Which has the lower trailing P/E, INCY or MDLN?: INCY has the lower trailing P/E: INCY trades at 16.37 and MDLN at 39.43. P/E is one valuation measure and does not by itself establish which business is cheaper.
Is INCY or MDLN more profitable?: INCY runs the higher net margin — INCY at 27.71% versus MDLN at 2.31%.

Go deeper

Full INCY analysis Full MDLN analysis Interactive comparison tool

Dig into the metrics

Incyte P/E ratio Medline P/E ratio Incyte ROE Medline ROE Incyte operating margin Medline operating margin Incyte revenue growth Medline revenue growth Incyte free cash flow Medline free cash flow

Incyte & Medline appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks Highest Operating Margin Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 20, 2026.