Immunome, Inc. (IMNM) vs Inspire Medical Systems, Inc. (INSP)
A side-by-side comparison of Immunome, Inc. and Inspire Medical Systems, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
IMNM
Immunome, Inc.
$20.57HealthcareDelayed quote: Oct 6, 2026, 11:25 AM EDT
INSP
Inspire Medical Systems, Inc.
$69.25HealthcareDelayed quote: Oct 6, 2026, 11:25 AM EDT
Total return — IMNM vs INSP
growth of $100 · dividends reinvested · last 6yIMNM +57.4% (+7.9%/yr)INSP -44.0% (-9.2%/yr)IMNM compounded faster over this window
IMNM INSP
IMNM vs INSP: by the numbers
- •INSP is the larger company ($2.00B vs $1.97B market cap).
- •INSP is profitable (15.03% net margin) while IMNM runs a net loss (-3059.99%).
Metrics side by side
Valuation
| Metric | IMNM | INSP |
|---|---|---|
| P/E ratio | N/A | 14.99 |
| Forward P/E | N/A | 57.98 |
| P/S ratio | N/A | 2.23 |
| P/B ratio | 3.74 | 2.43 |
| EV / EBITDA | N/A | 26.68 |
| FCF yield | N/A | 5.85% |
Profitability
| Metric | IMNM | INSP |
|---|---|---|
| Gross margin | 57.43% | 86.13% |
| Operating margin | -3084.76% | 6.02% |
| Net margin | -3059.99% | 15.03% |
| ROE | -48.43% | 16.36% |
| ROIC | -51.06% | 6.33% |
Growth (annualized)
| Metric | IMNM | INSP |
|---|---|---|
| Revenue CAGR (5Y) | N/A | 38.69% |
| Total return CAGR (5Y) | 2.88% | -21.38% |
Frequently asked
- Is IMNM or INSP more profitable?
- INSP runs the higher net margin — IMNM at -3059.99% versus INSP at 15.03%.
- How have IMNM and INSP total returns compared?
- Over the past 5 years, IMNM delivered 2.88% and INSP delivered -21.38% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Inspire Medical Systems P/E ratioImmunome ROEInspire Medical Systems ROEImmunome operating marginInspire Medical Systems operating marginImmunome revenue growthInspire Medical Systems revenue growthImmunome free cash flowInspire Medical Systems free cash flow
Immunome & Inspire Medical Systems appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.