Which has the lower trailing P/E, ICLR or PEN?

ICLR has the lower trailing P/E: ICLR trades at 38.04 and PEN at 78.02. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, ICLR or PEN?

Over the past five years, ICLR grew revenue faster — ICLR at a 20.93% CAGR versus PEN at 17.52%.

Is ICLR or PEN more profitable?

PEN runs the higher net margin — ICLR at 3.99% versus PEN at 10.67%.

How have ICLR and PEN total returns compared?

Over the past 10 years, ICLR delivered 7.67% and PEN delivered 15.37% annualized total return. Past performance doesn't predict future results.

ICON Public Limited Company (ICLR) vs Penumbra, Inc. (PEN)

A side-by-side comparison of ICON Public Limited Company and Penumbra, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 2, 2026. Differences are shown without an overall score or investment verdict.

ICLR

ICON Public Limited Company

$12.41B

$162.05HealthcareDelayed quote: Oct 2, 2026, 4:00 PM EDT

PEN

Penumbra, Inc.

$12.51B

$317.55HealthcareDelayed quote: Oct 2, 2026, 4:00 PM EDT

Total return — ICLR vs PEN

growth of $100 · dividends reinvested · last 10y

ICLR +112.9% (+7.8%/yr)PEN +327.8% (+15.6%/yr)PEN compounded faster over this window

ICLR PEN

ICLR vs PEN: by the numbers

•PEN is the larger company ($12.51B vs $12.41B market cap).
•ICLR trades at the lower trailing earnings multiple (38.04 vs 78.02 P/E), one valuation lens rather than an overall verdict.
•PEN converts more revenue to profit (10.67% vs 3.99% net margin).
•ICLR grew revenue faster over the past five years (20.93% vs 17.52% CAGR).

Metrics side by side

Valuation

Metric	ICLR	PEN
P/E ratio	38.04	78.02
Forward P/E	15.30	67.45
P/S ratio	1.50	8.31
P/B ratio	1.32	8.17
EV / EBITDA	10.60	61.21
FCF yield	10.85%	1.73%

Profitability

Metric	ICLR	PEN
Gross margin	21.85%	67.84%
Operating margin	10.15%	12.45%
Net margin	3.99%	10.67%
ROE	3.51%	10.49%
ROIC	4.80%	8.48%

Growth (annualized)

Metric	ICLR	PEN
Revenue CAGR (5Y)	20.93%	17.52%
EPS CAGR (5Y)	-14.23%	N/A
FCF CAGR (5Y)	22.10%	N/A
Total return CAGR (5Y)	-9.18%	3.83%

Frequently asked

Which has the lower trailing P/E, ICLR or PEN?: ICLR has the lower trailing P/E: ICLR trades at 38.04 and PEN at 78.02. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ICLR or PEN?: Over the past five years, ICLR grew revenue faster — ICLR at a 20.93% CAGR versus PEN at 17.52%.
Is ICLR or PEN more profitable?: PEN runs the higher net margin — ICLR at 3.99% versus PEN at 10.67%.
How have ICLR and PEN total returns compared?: Over the past 10 years, ICLR delivered 7.67% and PEN delivered 15.37% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ICLR analysis Full PEN analysis Interactive comparison tool

Dig into the metrics

ICON Public P/E ratio Penumbra P/E ratio ICON Public ROE Penumbra ROE ICON Public operating margin Penumbra operating margin ICON Public revenue growth Penumbra revenue growth ICON Public free cash flow Penumbra free cash flow

ICON Public & Penumbra appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 2, 2026.