ImmunityBio, Inc. (IBRX) vs Krystal Biotech, Inc. (KRYS)

A side-by-side comparison of ImmunityBio, Inc. and Krystal Biotech, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
ImmunityBio, Inc. logo
IBRX
ImmunityBio, Inc.
$10.33B
$9.86HealthcareDelayed quote: Oct 6, 2026, 1:55 PM EDT
Krystal Biotech, Inc. logo
KRYS
Krystal Biotech, Inc.
$9.61B
$325.92HealthcareDelayed quote: Oct 6, 2026, 1:55 PM EDT

Total return — IBRX vs KRYS

growth of $100 · dividends reinvested · last 9y
IBRX +74.5% (+6.4%/yr)KRYS +3047.1% (+46.7%/yr)KRYS compounded faster over this window
Log scale — wide-divergence pair
101001k10kStart $1002019202120232025$174$3,147
IBRX KRYS

IBRX vs KRYS: by the numbers

  • •IBRX is the larger company ($10.33B vs $9.61B market cap).
  • •KRYS is profitable (54.82% net margin) while IBRX runs a net loss (-598.56%).

Metrics side by side

Valuation

MetricIBRXKRYS
P/E ratioN/A40.84
Forward P/EN/A42.84
P/S ratio62.2821.81
P/B ratioN/A7.07
EV / EBITDAN/A44.96
FCF yieldN/A2.68%

Profitability

MetricIBRXKRYS
Gross margin94.63%93.34%
Operating margin-226.00%44.93%
Net margin-598.56%54.82%
ROEN/A17.77%
ROIC-45.63%14.41%

Growth (annualized)

MetricIBRXKRYS
Revenue CAGR (5Y)202.97%N/A
Total return CAGR (5Y)0.39%44.28%

Frequently asked

Is IBRX or KRYS more profitable?
KRYS runs the higher net margin — IBRX at -598.56% versus KRYS at 54.82%.
How have IBRX and KRYS total returns compared?
Over the past 5 years, IBRX delivered 0.39% and KRYS delivered 44.28% annualized total return. Past performance doesn't predict future results.

Go deeper

Full IBRX analysisFull KRYS analysisInteractive comparison tool

Dig into the metrics

Krystal Biotech P/E ratioImmunityBio ROEKrystal Biotech ROEImmunityBio operating marginKrystal Biotech operating marginImmunityBio revenue growthKrystal Biotech revenue growthImmunityBio free cash flowKrystal Biotech free cash flow

ImmunityBio & Krystal Biotech appear in these rankings

Fastest Revenue Growth StocksHighest Operating Margin Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.