Humana Inc. (HUM) vs Illumina, Inc. (ILMN)
A side-by-side comparison of Humana Inc. and Illumina, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 2, 2026. Differences are shown without an overall score or investment verdict.
HUM
Humana Inc.
$388.36HealthcareDelayed quote: Oct 2, 2026, 4:01 PM EDT
ILMN
Illumina, Inc.
$273.04HealthcareDelayed quote: Oct 2, 2026, 4:00 PM EDT
Total return — HUM vs ILMN
growth of $100 · dividends reinvested · last 10yHUM +134.0% (+8.9%/yr)ILMN +48.2% (+4.0%/yr)HUM compounded faster over this window
HUM ILMN
HUM vs ILMN: by the numbers
- •HUM is the larger company ($46.63B vs $41.31B market cap).
- •HUM trades at the lower trailing earnings multiple (36.78 vs 50.94 P/E), one valuation lens rather than an overall verdict.
- •ILMN converts more revenue to profit (18.36% vs 0.88% net margin).
- •HUM grew revenue faster over the past five years (12.61% vs 5.04% CAGR).
- •HUM pays a dividend (0.70% yield), while ILMN has no payments in the available dividend history.
Metrics side by side
Valuation
| Metric | HUM | ILMN |
|---|---|---|
| P/E ratio | 36.78 | 50.94 |
| Forward P/E | 42.41 | 51.00 |
| PEG ratio | N/A | 11.99 |
| P/S ratio | 0.32 | 9.19 |
| P/B ratio | 2.43 | 14.56 |
| EV / EBITDA | 19.47 | 35.22 |
| FCF yield | N/A | 2.27% |
Profitability
| Metric | HUM | ILMN |
|---|---|---|
| Gross margin | 13.65% | 66.79% |
| Operating margin | 1.39% | 20.97% |
| Net margin | 0.88% | 18.36% |
| ROE | 6.65% | 29.07% |
| ROIC | 4.52% | 13.74% |
Dividends
| Metric | HUM | ILMN |
|---|---|---|
| Dividend yield | 0.70% | N/A |
| Payout ratio | 25.14% | N/A |
Growth (annualized)
| Metric | HUM | ILMN |
|---|---|---|
| Revenue CAGR (5Y) | 12.61% | 5.04% |
| EPS CAGR (5Y) | -17.27% | 4.22% |
| FCF CAGR (5Y) | N/A | 1.03% |
| Total return CAGR (5Y) | 0.35% | -7.09% |
Frequently asked
- Which has the lower trailing P/E, HUM or ILMN?
- HUM has the lower trailing P/E: HUM trades at 36.78 and ILMN at 50.94. P/E is one valuation measure and does not by itself establish which business is cheaper.
- Which has grown faster, HUM or ILMN?
- Over the past five years, HUM grew revenue faster — HUM at a 12.61% CAGR versus ILMN at 5.04%.
- Does HUM or ILMN pay a bigger dividend?
- HUM pays a dividend (0.70% yield), while ILMN has no payments in the available dividend history.
- Is HUM or ILMN more profitable?
- ILMN runs the higher net margin — HUM at 0.88% versus ILMN at 18.36%.
- How have HUM and ILMN total returns compared?
- Over the past 10 years, HUM delivered 8.85% and ILMN delivered 4.17% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Humana P/E ratioIllumina P/E ratioHumana dividend yieldHumana ROEIllumina ROEHumana operating marginIllumina operating marginHumana revenue growthIllumina revenue growthHumana free cash flowIllumina free cash flow
Humana & Illumina appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 2, 2026.