Which has the lower trailing P/E, HSIC or TMDX?

TMDX has the lower trailing P/E: HSIC trades at 25.80 and TMDX at 24.55. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, HSIC or TMDX?

Over the past five years, TMDX grew revenue faster — HSIC at a 2.71% CAGR versus TMDX at 86.12%.

Is HSIC or TMDX more profitable?

TMDX runs the higher net margin — HSIC at 2.96% versus TMDX at 22.69%.

How have HSIC and TMDX total returns compared?

Over the past 5 years, HSIC delivered 3.41% and TMDX delivered 28.61% annualized total return. Past performance doesn't predict future results.

Henry Schein, Inc. (HSIC) vs TransMedics Group, Inc. (TMDX)

A side-by-side comparison of Henry Schein, Inc. and TransMedics Group, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 23, 2026. Differences are shown without an overall score or investment verdict.

HSIC

Henry Schein, Inc.

$10.08B

$88.50HealthcareAt close: Aug 21, 2026, 4:00 PM ET

TMDX

TransMedics Group, Inc.

$3.28B

$94.77HealthcareAt close: Aug 21, 2026, 4:00 PM ET

Total return — HSIC vs TMDX

growth of $100 · dividends reinvested · last 7y

HSIC +41.7% (+5.1%/yr)TMDX +323.8% (+22.9%/yr)TMDX compounded faster over this window

HSIC TMDX

HSIC vs TMDX: by the numbers

•HSIC is the larger company ($10.08B vs $3.28B market cap).
•TMDX trades at the lower trailing earnings multiple (24.55 vs 25.80 P/E), one valuation lens rather than an overall verdict.
•TMDX converts more revenue to profit (22.69% vs 2.96% net margin).
•TMDX grew revenue faster over the past five years (86.12% vs 2.71% CAGR).

Metrics side by side

Valuation

Metric	HSIC	TMDX
P/E ratio	25.80	24.55
Forward P/E	16.44	63.34
P/S ratio	0.74	5.77
P/B ratio	3.21	7.45
EV / EBITDA	12.68	36.03
FCF yield	5.32%	2.05%

Profitability

Metric	HSIC	TMDX
Gross margin	30.31%	58.69%
Operating margin	5.69%	12.21%
Net margin	2.96%	22.69%
ROE	12.77%	29.28%
ROIC	6.53%	5.87%

Growth (annualized)

Metric	HSIC	TMDX
Revenue CAGR (5Y)	2.71%	86.12%
EPS CAGR (5Y)	3.14%	N/A
FCF CAGR (5Y)	0.82%	N/A
Total return CAGR (5Y)	3.19%	28.61%

Frequently asked

Which has the lower trailing P/E, HSIC or TMDX?: TMDX has the lower trailing P/E: HSIC trades at 25.80 and TMDX at 24.55. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, HSIC or TMDX?: Over the past five years, TMDX grew revenue faster — HSIC at a 2.71% CAGR versus TMDX at 86.12%.
Is HSIC or TMDX more profitable?: TMDX runs the higher net margin — HSIC at 2.96% versus TMDX at 22.69%.
How have HSIC and TMDX total returns compared?: Over the past 5 years, HSIC delivered 3.41% and TMDX delivered 28.61% annualized total return. Past performance doesn't predict future results.

Go deeper

Full HSIC analysis Full TMDX analysis Interactive comparison tool

Dig into the metrics

Henry Schein P/E ratio TransMedics P/E ratio Henry Schein ROE TransMedics ROE Henry Schein operating margin TransMedics operating margin Henry Schein revenue growth TransMedics revenue growth Henry Schein free cash flow TransMedics free cash flow

Henry Schein & TransMedics appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 23, 2026.