Which has the lower trailing P/E, HSIC or RGEN?

HSIC has the lower trailing P/E: HSIC trades at 24.73 and RGEN at 239.53. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, HSIC or RGEN?

Over the past five years, RGEN grew revenue faster — HSIC at a 2.71% CAGR versus RGEN at 9.08%.

Is HSIC or RGEN more profitable?

RGEN runs the higher net margin — HSIC at 2.96% versus RGEN at 5.29%.

How have HSIC and RGEN total returns compared?

Over the past 10 years, HSIC delivered 2.90% and RGEN delivered 20.13% annualized total return. Past performance doesn't predict future results.

Henry Schein, Inc. (HSIC) vs Repligen Corporation (RGEN)

A side-by-side comparison of Henry Schein, Inc. and Repligen Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

HSIC

Henry Schein, Inc.

$9.66B

$84.84HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

RGEN

Repligen Corporation

$9.87B

$174.86HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — HSIC vs RGEN

growth of $100 · dividends reinvested · last 10y

HSIC +31.7% (+2.8%/yr)RGEN +528.7% (+20.2%/yr)RGEN compounded faster over this window

HSIC RGEN

HSIC vs RGEN: by the numbers

•RGEN is the larger company ($9.87B vs $9.66B market cap).
•HSIC trades at the lower trailing earnings multiple (24.73 vs 239.53 P/E), one valuation lens rather than an overall verdict.
•RGEN converts more revenue to profit (5.29% vs 2.96% net margin).
•RGEN grew revenue faster over the past five years (9.08% vs 2.71% CAGR).

Metrics side by side

Valuation

Metric	HSIC	RGEN
P/E ratio	24.73	239.53
Forward P/E	15.75	84.92
PEG ratio	7.83	N/A
P/S ratio	0.71	12.57
P/B ratio	3.06	4.67
EV / EBITDA	12.25	67.03
FCF yield	5.58%	1.12%

Profitability

Metric	HSIC	RGEN
Gross margin	30.31%	51.05%
Operating margin	5.69%	8.32%
Net margin	2.96%	5.29%
ROE	12.77%	1.97%
ROIC	6.53%	1.85%

Growth (annualized)

Metric	HSIC	RGEN
Revenue CAGR (5Y)	2.71%	9.08%
EPS CAGR (5Y)	3.14%	-5.26%
FCF CAGR (5Y)	0.82%	22.49%
Total return CAGR (5Y)	1.39%	-6.86%

Frequently asked

Which has the lower trailing P/E, HSIC or RGEN?: HSIC has the lower trailing P/E: HSIC trades at 24.73 and RGEN at 239.53. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, HSIC or RGEN?: Over the past five years, RGEN grew revenue faster — HSIC at a 2.71% CAGR versus RGEN at 9.08%.
Is HSIC or RGEN more profitable?: RGEN runs the higher net margin — HSIC at 2.96% versus RGEN at 5.29%.
How have HSIC and RGEN total returns compared?: Over the past 10 years, HSIC delivered 2.90% and RGEN delivered 20.13% annualized total return. Past performance doesn't predict future results.

Go deeper

Full HSIC analysis Full RGEN analysis Interactive comparison tool

Dig into the metrics

Henry Schein P/E ratio Repligen P/E ratio Henry Schein ROE Repligen ROE Henry Schein operating margin Repligen operating margin Henry Schein revenue growth Repligen revenue growth Henry Schein free cash flow Repligen free cash flow

Henry Schein & Repligen appear in these rankings

Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.