Harmony Biosciences Holdings, Inc. (HRMY) vs Nurix Therapeutics, Inc. (NRIX)
A side-by-side comparison of Harmony Biosciences Holdings, Inc. and Nurix Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
HRMY
Harmony Biosciences Holdings, Inc.
$39.50HealthcareDelayed quote: Oct 6, 2026, 2:20 PM EDT
NRIX
Nurix Therapeutics, Inc.
$22.55HealthcareDelayed quote: Oct 6, 2026, 2:20 PM EDT
Total return — HRMY vs NRIX
growth of $100 · dividends reinvested · last 6yHRMY +7.9% (+1.3%/yr)NRIX -21.7% (-4.0%/yr)HRMY compounded faster over this window
HRMY NRIX
HRMY vs NRIX: by the numbers
- •NRIX is the larger company ($2.34B vs $2.29B market cap).
- •HRMY is profitable (18.88% net margin) while NRIX runs a net loss (-928.44%).
- •HRMY grew revenue faster over the past five years (32.47% vs 9.96% CAGR).
Metrics side by side
Valuation
| Metric | HRMY | NRIX |
|---|---|---|
| P/E ratio | 12.82 | N/A |
| Forward P/E | 10.02 | N/A |
| P/S ratio | 2.38 | 63.65 |
| P/B ratio | 2.29 | 5.81 |
| EV / EBITDA | 7.39 | N/A |
| FCF yield | 15.52% | N/A |
Profitability
| Metric | HRMY | NRIX |
|---|---|---|
| Gross margin | 75.42% | 77.55% |
| Operating margin | 24.03% | -340.16% |
| Net margin | 18.88% | -928.44% |
| ROE | 18.14% | -84.78% |
| ROIC | 14.96% | -77.92% |
Growth (annualized)
| Metric | HRMY | NRIX |
|---|---|---|
| Revenue CAGR (5Y) | 32.47% | 9.96% |
| FCF CAGR (5Y) | 48.43% | N/A |
| Total return CAGR (5Y) | 0.91% | -5.51% |
Frequently asked
- Which has grown faster, HRMY or NRIX?
- Over the past five years, HRMY grew revenue faster — HRMY at a 32.47% CAGR versus NRIX at 9.96%.
- Is HRMY or NRIX more profitable?
- HRMY runs the higher net margin — HRMY at 18.88% versus NRIX at -928.44%.
- How have HRMY and NRIX total returns compared?
- Over the past 5 years, HRMY delivered 0.91% and NRIX delivered -5.51% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Harmony Biosciences P/E ratioHarmony Biosciences ROENurix Therapeutics ROEHarmony Biosciences operating marginNurix Therapeutics operating marginHarmony Biosciences revenue growthNurix Therapeutics revenue growthHarmony Biosciences free cash flowNurix Therapeutics free cash flow
Harmony Biosciences & Nurix Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.