Harmony Biosciences Holdings, Inc. (HRMY) vs Nurix Therapeutics, Inc. (NRIX)

A side-by-side comparison of Harmony Biosciences Holdings, Inc. and Nurix Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — HRMY vs NRIX

growth of $100 · dividends reinvested · last 6y
HRMY +7.9% (+1.3%/yr)NRIX -21.7% (-4.0%/yr)HRMY compounded faster over this window
50100150Start $100202120222023202420252026$108$78
HRMY NRIX

HRMY vs NRIX: by the numbers

  • •NRIX is the larger company ($2.34B vs $2.29B market cap).
  • •HRMY is profitable (18.88% net margin) while NRIX runs a net loss (-928.44%).
  • •HRMY grew revenue faster over the past five years (32.47% vs 9.96% CAGR).

Metrics side by side

Valuation

MetricHRMYNRIX
P/E ratio12.82N/A
Forward P/E10.02N/A
P/S ratio2.3863.65
P/B ratio2.295.81
EV / EBITDA7.39N/A
FCF yield15.52%N/A

Profitability

MetricHRMYNRIX
Gross margin75.42%77.55%
Operating margin24.03%-340.16%
Net margin18.88%-928.44%
ROE18.14%-84.78%
ROIC14.96%-77.92%

Growth (annualized)

MetricHRMYNRIX
Revenue CAGR (5Y)32.47%9.96%
FCF CAGR (5Y)48.43%N/A
Total return CAGR (5Y)0.91%-5.51%

Frequently asked

Which has grown faster, HRMY or NRIX?
Over the past five years, HRMY grew revenue faster — HRMY at a 32.47% CAGR versus NRIX at 9.96%.
Is HRMY or NRIX more profitable?
HRMY runs the higher net margin — HRMY at 18.88% versus NRIX at -928.44%.
How have HRMY and NRIX total returns compared?
Over the past 5 years, HRMY delivered 0.91% and NRIX delivered -5.51% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.