Harmony Biosciences Holdings, Inc. (HRMY) vs Disc Medicine, Inc. (IRON)

A side-by-side comparison of Harmony Biosciences Holdings, Inc. and Disc Medicine, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
Harmony Biosciences Holdings, Inc. logo
HRMY
Harmony Biosciences Holdings, Inc.
$2.31B
$39.94HealthcareDelayed quote: Oct 6, 2026, 12:00 PM EDT
Disc Medicine, Inc. logo
IRON
Disc Medicine, Inc.
$2.46B
$63.98HealthcareDelayed quote: Oct 6, 2026, 12:00 PM EDT

Total return — HRMY vs IRON

growth of $100 · dividends reinvested · last 6y
HRMY +7.9% (+1.3%/yr)IRON -38.5% (-7.8%/yr)HRMY compounded faster over this window
050100150Start $100202120222023202420252026$108$61
HRMY IRON

HRMY vs IRON: by the numbers

  • •IRON is the larger company ($2.46B vs $2.31B market cap).
  • •HRMY is profitable (18.88% net margin) while IRON runs a net loss (0.00%).

Metrics side by side

Valuation

MetricHRMYIRON
P/E ratio12.97N/A
Forward P/E10.13N/A
P/S ratio2.41N/A
P/B ratio2.313.81
EV / EBITDA7.49N/A
FCF yield15.35%N/A

Profitability

MetricHRMYIRON
Gross margin75.42%0.00%
Operating margin24.03%0.00%
Net margin18.88%0.00%
ROE18.14%-38.17%
ROIC14.96%-38.21%

Growth (annualized)

MetricHRMYIRON
Revenue CAGR (5Y)32.47%N/A
FCF CAGR (5Y)48.43%N/A
Total return CAGR (5Y)0.91%10.70%

Frequently asked

Is HRMY or IRON more profitable?
HRMY runs the higher net margin — HRMY at 18.88% versus IRON at 0.00%.
How have HRMY and IRON total returns compared?
Over the past 5 years, HRMY delivered 0.91% and IRON delivered 10.70% annualized total return. Past performance doesn't predict future results.

Go deeper

Full HRMY analysisFull IRON analysisInteractive comparison tool

Dig into the metrics

Harmony Biosciences P/E ratioHarmony Biosciences ROEDisc Medicine ROEHarmony Biosciences operating marginDisc Medicine operating marginHarmony Biosciences revenue growthDisc Medicine revenue growthHarmony Biosciences free cash flowDisc Medicine free cash flow

Harmony Biosciences & Disc Medicine appear in these rankings

Fastest Revenue Growth StocksHighest FCF Yield StocksLowest P/E Ratio Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.