HCA Healthcare, Inc. (HCA) vs Vertex Pharmaceuticals Incorporated (VRTX)
HCA leads on 8 of 15 compared metrics.
A side-by-side comparison of HCA Healthcare, Inc. and Vertex Pharmaceuticals Incorporated across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 16, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
HCA
HCA Healthcare, Inc.
$396.93Healthcare
VRTX
Vertex Pharmaceuticals Incorporated
$450.46Healthcare
Total return — HCA vs VRTX
growth of $100 · last 15yHCA +1179.6%VRTX +897.8%HCA compounded faster
HCA VRTX
HCA vs VRTX: by the numbers
- •VRTX is the larger company ($113.82B vs $88.05B market cap).
- •HCA trades at the lower earnings multiple (13.65 vs 26.72 P/E).
- •VRTX converts more revenue to profit (35.40% vs 8.89% net margin).
- •VRTX grew revenue faster over the past five years (13.82% vs 7.73% CAGR).
- •HCA pays a dividend (0.76% yield) while VRTX does not currently pay one.
Which is better, HCA or VRTX?
Metric tally: HCA 8 · VRTX 7It depends on what you're optimizing for:
ValueHCA(lower P/E)
GrowthVRTX(faster 5Y revenue CAGR)
QualityHCA(higher ROIC)
Metrics side by side
Valuation
| Metric | HCA | VRTX |
|---|---|---|
| P/E ratio | 13.65● | 26.72 |
| Forward P/E | 11.96● | 20.84 |
| P/S ratio | 1.18● | 9.42 |
| P/B ratio | — | 5.96 |
| PEG ratio | 0.56● | 3.27 |
| EV / EBITDA | 8.86● | 20.77 |
| FCF yield | 8.81%● | 3.21% |
Profitability
| Metric | HCA | VRTX |
|---|---|---|
| Gross margin | 34.92% | 86.28%● |
| Operating margin | 15.67% | 38.97%● |
| Net margin | 8.89% | 35.40%● |
| ROE | -112.56% | 22.41%● |
| ROIC | 18.53%● | 18.12% |
Dividends
| Metric | HCA | VRTX |
|---|---|---|
| Dividend yield | 0.76% | — |
| Payout ratio | 10.48% | — |
Growth (annualized)
| Metric | HCA | VRTX |
|---|---|---|
| Revenue CAGR (5Y) | 7.73% | 13.82%● |
| EPS CAGR (5Y) | 20.90%● | 8.17% |
| FCF CAGR (5Y) | 1.92% | 4.01%● |
| Total return CAGR (5Y) | 14.89% | 18.98%● |
Frequently asked
- Which is better, HCA or VRTX?
- It depends on your goal. value: HCA (lower P/E); growth: VRTX (faster 5Y revenue CAGR); quality: HCA (higher ROIC). Across all compared metrics, HCA leads 8 to 7.
- Is HCA or VRTX cheaper?
- On trailing earnings, HCA is cheaper: HCA trades at a 13.65 P/E and VRTX at 26.72.
- Which has grown faster, HCA or VRTX?
- Over the past five years, VRTX grew revenue faster — HCA at a 7.73% CAGR versus VRTX at 13.82%.
- Does HCA or VRTX pay a bigger dividend?
- HCA pays a dividend (0.76% yield) while VRTX does not currently pay one.
- Is HCA or VRTX more profitable?
- VRTX runs the higher net margin — HCA at 8.89% versus VRTX at 35.40%.
- Which has been the better investment, HCA or VRTX?
- Over the past 10-year, HCA delivered the higher annualized total return — HCA at 18.63% versus VRTX at 17.33%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
HCA Healthcare P/E ratioVertex Pharmaceuticals P/E ratioHCA Healthcare dividend yieldVertex Pharmaceuticals dividend yieldHCA Healthcare ROEVertex Pharmaceuticals ROEHCA Healthcare operating marginVertex Pharmaceuticals operating marginHCA Healthcare revenue growthVertex Pharmaceuticals revenue growthHCA Healthcare free cash flowVertex Pharmaceuticals free cash flow
HCA Healthcare & Vertex Pharmaceuticals appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 16, 2026.