HCA Healthcare, Inc. (HCA) vs Vertex Pharmaceuticals Incorporated (VRTX)

HCA leads on 8 of 15 compared metrics.

A side-by-side comparison of HCA Healthcare, Inc. and Vertex Pharmaceuticals Incorporated across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 16, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Compare

Total return — HCA vs VRTX

growth of $100 · last 15y
HCA +1179.6%VRTX +897.8%HCA compounded faster
05001k2kStart $10020142017202020232026$1,280$998
HCA VRTX

HCA vs VRTX: by the numbers

  • VRTX is the larger company ($113.82B vs $88.05B market cap).
  • HCA trades at the lower earnings multiple (13.65 vs 26.72 P/E).
  • VRTX converts more revenue to profit (35.40% vs 8.89% net margin).
  • VRTX grew revenue faster over the past five years (13.82% vs 7.73% CAGR).
  • HCA pays a dividend (0.76% yield) while VRTX does not currently pay one.

Which is better, HCA or VRTX?

Metric tally: HCA 8 · VRTX 7

It depends on what you're optimizing for:

ValueHCA(lower P/E)
GrowthVRTX(faster 5Y revenue CAGR)
QualityHCA(higher ROIC)

Metrics side by side

Valuation

MetricHCAVRTX
P/E ratio13.6526.72
Forward P/E11.9620.84
P/S ratio1.189.42
P/B ratio5.96
PEG ratio0.563.27
EV / EBITDA8.8620.77
FCF yield8.81%3.21%

Profitability

MetricHCAVRTX
Gross margin34.92%86.28%
Operating margin15.67%38.97%
Net margin8.89%35.40%
ROE-112.56%22.41%
ROIC18.53%18.12%

Dividends

MetricHCAVRTX
Dividend yield0.76%
Payout ratio10.48%

Growth (annualized)

MetricHCAVRTX
Revenue CAGR (5Y)7.73%13.82%
EPS CAGR (5Y)20.90%8.17%
FCF CAGR (5Y)1.92%4.01%
Total return CAGR (5Y)14.89%18.98%

Frequently asked

Which is better, HCA or VRTX?
It depends on your goal. value: HCA (lower P/E); growth: VRTX (faster 5Y revenue CAGR); quality: HCA (higher ROIC). Across all compared metrics, HCA leads 8 to 7.
Is HCA or VRTX cheaper?
On trailing earnings, HCA is cheaper: HCA trades at a 13.65 P/E and VRTX at 26.72.
Which has grown faster, HCA or VRTX?
Over the past five years, VRTX grew revenue faster — HCA at a 7.73% CAGR versus VRTX at 13.82%.
Does HCA or VRTX pay a bigger dividend?
HCA pays a dividend (0.76% yield) while VRTX does not currently pay one.
Is HCA or VRTX more profitable?
VRTX runs the higher net margin — HCA at 8.89% versus VRTX at 35.40%.
Which has been the better investment, HCA or VRTX?
Over the past 10-year, HCA delivered the higher annualized total return — HCA at 18.63% versus VRTX at 17.33%. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 16, 2026.