Halozyme Therapeutics, Inc. (HALO) vs Summit Therapeutics Inc. (SMMT)
A side-by-side comparison of Halozyme Therapeutics, Inc. and Summit Therapeutics Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
HALO
Halozyme Therapeutics, Inc.
$109.94HealthcareDelayed quote: Oct 6, 2026, 1:20 PM EDT
SMMT
Summit Therapeutics Inc.
$16.97HealthcareDelayed quote: Oct 6, 2026, 1:15 PM EDT
Total return — HALO vs SMMT
growth of $100 · dividends reinvested · last 10yHALO +779.9% (+24.3%/yr)SMMT +99.7% (+7.2%/yr)HALO compounded faster over this window
HALO SMMT
HALO vs SMMT: by the numbers
- •SMMT is the larger company ($13.54B vs $13.04B market cap).
- •HALO is profitable (24.86% net margin) while SMMT runs a net loss (0.00%).
Metrics side by side
Valuation
| Metric | HALO | SMMT |
|---|---|---|
| P/E ratio | 32.82 | N/A |
| Forward P/E | 13.07 | N/A |
| PEG ratio | 1.43 | N/A |
| P/S ratio | 7.84 | N/A |
| P/B ratio | 90.85 | 21.49 |
| EV / EBITDA | 14.24 | N/A |
| FCF yield | 6.18% | N/A |
Profitability
| Metric | HALO | SMMT |
|---|---|---|
| Gross margin | 78.18% | 0.00% |
| Operating margin | 56.77% | 0.00% |
| Net margin | 24.86% | 0.00% |
| ROE | 288.13% | -135.89% |
| ROIC | 27.42% | -134.14% |
Growth (annualized)
| Metric | HALO | SMMT |
|---|---|---|
| Revenue CAGR (5Y) | 32.18% | N/A |
| EPS CAGR (5Y) | 22.68% | N/A |
| FCF CAGR (5Y) | 40.08% | N/A |
| Total return CAGR (5Y) | 22.18% | 28.09% |
Frequently asked
- Is HALO or SMMT more profitable?
- HALO runs the higher net margin — HALO at 24.86% versus SMMT at 0.00%.
- How have HALO and SMMT total returns compared?
- Over the past 10 years, HALO delivered 24.30% and SMMT delivered 1.87% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Halozyme Therapeutics P/E ratioHalozyme Therapeutics ROESummit Therapeutics ROEHalozyme Therapeutics operating marginSummit Therapeutics operating marginHalozyme Therapeutics revenue growthSummit Therapeutics revenue growthHalozyme Therapeutics free cash flowSummit Therapeutics free cash flow
Halozyme Therapeutics & Summit Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.