Halozyme Therapeutics, Inc. (HALO) vs Jazz Pharmaceuticals plc (JAZZ)

A side-by-side comparison of Halozyme Therapeutics, Inc. and Jazz Pharmaceuticals plc across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — HALO vs JAZZ

growth of $100 · dividends reinvested · last 10y
HALO +779.9% (+24.3%/yr)JAZZ +91.9% (+6.7%/yr)HALO compounded faster over this window
200400600800Start $10020182020202220242026$880$192
HALO JAZZ

HALO vs JAZZ: by the numbers

  • •JAZZ is the larger company ($14.54B vs $13.01B market cap).
  • •JAZZ trades at the lower trailing earnings multiple (15.82 vs 32.75 P/E), one valuation lens rather than an overall verdict.
  • •HALO converts more revenue to profit (24.86% vs 20.45% net margin).
  • •HALO grew revenue faster over the past five years (32.18% vs 11.87% CAGR).

Metrics side by side

Valuation

MetricHALOJAZZ
P/E ratio32.7515.82
Forward P/E13.049.27
PEG ratio1.43N/A
P/S ratio7.823.16
P/B ratio90.663.03
EV / EBITDA14.228.74
FCF yield6.19%10.61%

Profitability

MetricHALOJAZZ
Gross margin78.18%84.67%
Operating margin56.77%5.26%
Net margin24.86%20.45%
ROE288.13%19.59%
ROIC27.42%14.48%

Growth (annualized)

MetricHALOJAZZ
Revenue CAGR (5Y)32.18%11.87%
EPS CAGR (5Y)22.68%N/A
FCF CAGR (5Y)40.08%15.39%
Total return CAGR (5Y)22.18%13.01%

Frequently asked

Which has the lower trailing P/E, HALO or JAZZ?
JAZZ has the lower trailing P/E: HALO trades at 32.75 and JAZZ at 15.82. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, HALO or JAZZ?
Over the past five years, HALO grew revenue faster — HALO at a 32.18% CAGR versus JAZZ at 11.87%.
Is HALO or JAZZ more profitable?
HALO runs the higher net margin — HALO at 24.86% versus JAZZ at 20.45%.
How have HALO and JAZZ total returns compared?
Over the past 10 years, HALO delivered 24.30% and JAZZ delivered 6.58% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.