Halozyme Therapeutics, Inc. (HALO) vs Jazz Pharmaceuticals plc (JAZZ)
A side-by-side comparison of Halozyme Therapeutics, Inc. and Jazz Pharmaceuticals plc across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
HALO
Halozyme Therapeutics, Inc.
$109.72HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
JAZZ
Jazz Pharmaceuticals plc
$231.39HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — HALO vs JAZZ
growth of $100 · dividends reinvested · last 10yHALO +779.9% (+24.3%/yr)JAZZ +91.9% (+6.7%/yr)HALO compounded faster over this window
HALO JAZZ
HALO vs JAZZ: by the numbers
- •JAZZ is the larger company ($14.54B vs $13.01B market cap).
- •JAZZ trades at the lower trailing earnings multiple (15.82 vs 32.75 P/E), one valuation lens rather than an overall verdict.
- •HALO converts more revenue to profit (24.86% vs 20.45% net margin).
- •HALO grew revenue faster over the past five years (32.18% vs 11.87% CAGR).
Metrics side by side
Valuation
| Metric | HALO | JAZZ |
|---|---|---|
| P/E ratio | 32.75 | 15.82 |
| Forward P/E | 13.04 | 9.27 |
| PEG ratio | 1.43 | N/A |
| P/S ratio | 7.82 | 3.16 |
| P/B ratio | 90.66 | 3.03 |
| EV / EBITDA | 14.22 | 8.74 |
| FCF yield | 6.19% | 10.61% |
Profitability
| Metric | HALO | JAZZ |
|---|---|---|
| Gross margin | 78.18% | 84.67% |
| Operating margin | 56.77% | 5.26% |
| Net margin | 24.86% | 20.45% |
| ROE | 288.13% | 19.59% |
| ROIC | 27.42% | 14.48% |
Growth (annualized)
| Metric | HALO | JAZZ |
|---|---|---|
| Revenue CAGR (5Y) | 32.18% | 11.87% |
| EPS CAGR (5Y) | 22.68% | N/A |
| FCF CAGR (5Y) | 40.08% | 15.39% |
| Total return CAGR (5Y) | 22.18% | 13.01% |
Frequently asked
- Which has the lower trailing P/E, HALO or JAZZ?
- JAZZ has the lower trailing P/E: HALO trades at 32.75 and JAZZ at 15.82. P/E is one valuation measure and does not by itself establish which business is cheaper.
- Which has grown faster, HALO or JAZZ?
- Over the past five years, HALO grew revenue faster — HALO at a 32.18% CAGR versus JAZZ at 11.87%.
- Is HALO or JAZZ more profitable?
- HALO runs the higher net margin — HALO at 24.86% versus JAZZ at 20.45%.
- How have HALO and JAZZ total returns compared?
- Over the past 10 years, HALO delivered 24.30% and JAZZ delivered 6.58% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Halozyme Therapeutics P/E ratioJazz Pharmaceuticals P/E ratioHalozyme Therapeutics ROEJazz Pharmaceuticals ROEHalozyme Therapeutics operating marginJazz Pharmaceuticals operating marginHalozyme Therapeutics revenue growthJazz Pharmaceuticals revenue growthHalozyme Therapeutics free cash flowJazz Pharmaceuticals free cash flow
Halozyme Therapeutics & Jazz Pharmaceuticals appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.