GSK plc (GSK) vs Regeneron Pharmaceuticals, Inc. (REGN)

A side-by-side comparison of GSK plc and Regeneron Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 13, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnGSK vs REGN

growth of $100 · dividends reinvested · last 10y
GSK +76.2% (+5.8%/yr)REGN +97.4% (+7.0%/yr)REGN compounded faster over this window
100150200250300Start $10020182020202220242026$176$197
GSK REGN

GSK vs REGN: by the numbers

  • GSK is the larger company ($100.20B vs $79.75B market cap).
  • GSK trades at the lower trailing earnings multiple (15.81 vs 19.15 P/E), one valuation lens rather than an overall verdict.
  • REGN converts more revenue to profit (27.86% vs 14.52% net margin).
  • REGN grew revenue faster over the past five years (4.64% vs 1.38% CAGR).
  • GSK pays the higher dividend yield (3.78% vs 0.47%).

Metrics side by side

Valuation

MetricGSKREGN
P/E ratio15.8119.15
Forward P/EN/A14.20
P/S ratio2.265.13
P/B ratio4.312.51
EV / EBITDA8.0817.62
FCF yield9.31%4.42%

Profitability

MetricGSKREGN
Gross margin72.71%84.86%
Operating margin20.72%25.56%
Net margin14.52%27.86%
ROE27.67%13.65%
ROIC13.95%9.19%

Dividends

MetricGSKREGN
Dividend yield3.78%0.47%
Payout ratio57.45%9.15%

Growth (annualized)

MetricGSKREGN
Revenue CAGR (5Y)1.38%4.64%
EPS CAGR (5Y)-0.71%5.70%
FCF CAGR (5Y)-2.45%15.77%
Total return CAGR (5Y)8.21%3.93%

Frequently asked

Which has the lower trailing P/E, GSK or REGN?
GSK has the lower trailing P/E: GSK trades at 15.81 and REGN at 19.15. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, GSK or REGN?
Over the past five years, REGN grew revenue faster — GSK at a 1.38% CAGR versus REGN at 4.64%.
Does GSK or REGN pay a bigger dividend?
GSK yields 3.78% and REGN yields 0.47% based on trailing dividends and the latest price.
Is GSK or REGN more profitable?
REGN runs the higher net margin — GSK at 14.52% versus REGN at 27.86%.
How have GSK and REGN total returns compared?
Over the past 10 years, GSK delivered 6.11% and REGN delivered 7.45% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 13, 2026.