Is GRAL or LNTH more profitable?

LNTH runs the higher net margin — GRAL at -236.95% versus LNTH at 17.69%.

GRAIL Inc. (GRAL) vs Lantheus Holdings, Inc. (LNTH)

A side-by-side comparison of GRAIL Inc. and Lantheus Holdings, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

GRAL

GRAIL Inc.

$6.06B

$141.22HealthcareDelayed quote: Oct 6, 2026, 11:10 AM EDT

LNTH

Lantheus Holdings, Inc.

$6.52B

$100.12HealthcareDelayed quote: Oct 6, 2026, 11:10 AM EDT

Total return — GRAL vs LNTH

growth of $100 · dividends reinvested · last 2y

GRAL +1028.0% (+235.9%/yr)LNTH +24.5% (+11.6%/yr)GRAL compounded faster over this window

Log scale — wide-divergence pair

GRAL LNTH

GRAL vs LNTH: by the numbers

•LNTH is the larger company ($6.52B vs $6.06B market cap).
•LNTH is profitable (17.69% net margin) while GRAL runs a net loss (-236.95%).

Metrics side by side

Valuation

Metric	GRAL	LNTH
P/E ratio	N/A	24.18
Forward P/E	N/A	18.49
P/S ratio	36.67	4.19
P/B ratio	2.38	4.97
EV / EBITDA	N/A	17.02
FCF yield	N/A	5.95%

Profitability

Metric	GRAL	LNTH
Gross margin	-42.52%	60.14%
Operating margin	-362.95%	19.43%
Net margin	-236.95%	17.69%
ROE	-15.40%	20.99%
ROIC	-20.26%	11.03%

Growth (annualized)

Metric	GRAL	LNTH
Revenue CAGR (5Y)	N/A	32.84%
FCF CAGR (5Y)	N/A	59.88%
Total return CAGR (5Y)	N/A	31.73%

Frequently asked

Is GRAL or LNTH more profitable?: LNTH runs the higher net margin — GRAL at -236.95% versus LNTH at 17.69%.

Go deeper

Full GRAL analysis Full LNTH analysis Interactive comparison tool

Dig into the metrics

Lantheus P/E ratio GRAIL ROE Lantheus ROE GRAIL operating margin Lantheus operating margin GRAIL revenue growth Lantheus revenue growth GRAIL free cash flow Lantheus free cash flow

GRAIL & Lantheus appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.