Globus Medical, Inc. (GMED) vs Madrigal Pharmaceuticals, Inc. (MDGL)

A side-by-side comparison of Globus Medical, Inc. and Madrigal Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
Globus Medical, Inc. logo
GMED
Globus Medical, Inc.
$10.37B
$76.88HealthcareDelayed quote: Oct 6, 2026, 2:20 PM EDT
Madrigal Pharmaceuticals, Inc. logo
MDGL
Madrigal Pharmaceuticals, Inc.
$11.56B
$500.28HealthcareDelayed quote: Oct 6, 2026, 2:20 PM EDT

Total return — GMED vs MDGL

growth of $100 · dividends reinvested · last 10y
GMED +239.1% (+13.0%/yr)MDGL +2930.2% (+40.7%/yr)MDGL compounded faster over this window
Log scale — wide-divergence pair
101001k10kStart $10020182020202220242026$339$3,030
GMED MDGL

GMED vs MDGL: by the numbers

  • •MDGL is the larger company ($11.56B vs $10.37B market cap).
  • •GMED is profitable (17.03% net margin) while MDGL runs a net loss (-25.32%).

Metrics side by side

Valuation

MetricGMEDMDGL
P/E ratio19.76N/A
Forward P/E15.37N/A
PEG ratio0.63N/A
P/S ratio3.309.00
P/B ratio2.1722.07
EV / EBITDA10.68N/A
FCF yield7.24%N/A

Profitability

MetricGMEDMDGL
Gross margin68.55%91.48%
Operating margin20.75%-25.13%
Net margin17.03%-25.32%
ROE11.23%-62.07%
ROIC10.49%-37.02%

Growth (annualized)

MetricGMEDMDGL
Revenue CAGR (5Y)27.65%N/A
EPS CAGR (5Y)30.79%N/A
FCF CAGR (5Y)29.93%N/A
Total return CAGR (5Y)-0.44%44.41%

Frequently asked

Is GMED or MDGL more profitable?
GMED runs the higher net margin — GMED at 17.03% versus MDGL at -25.32%.
How have GMED and MDGL total returns compared?
Over the past 10 years, GMED delivered 12.82% and MDGL delivered 41.50% annualized total return. Past performance doesn't predict future results.

Go deeper

Full GMED analysisFull MDGL analysisInteractive comparison tool

Dig into the metrics

Globus Medical P/E ratioGlobus Medical ROEMadrigal Pharmaceuticals ROEGlobus Medical operating marginMadrigal Pharmaceuticals operating marginGlobus Medical revenue growthMadrigal Pharmaceuticals revenue growthGlobus Medical free cash flowMadrigal Pharmaceuticals free cash flow

Globus Medical & Madrigal Pharmaceuticals appear in these rankings

Fastest Revenue Growth StocksHighest FCF Yield StocksHighest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.