Gilead Sciences, Inc. (GILD) vs Stryker Corporation (SYK)

GILD leads on 13 of 17 compared metrics.

A side-by-side comparison of Gilead Sciences, Inc. and Stryker Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 17, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Compare

Total return — GILD vs SYK

growth of $100 · last 30y
GILD +16647.7%SYK +4798.7%GILD compounded faster
05k10k15k20kStart $100200120062011201620212026$16,748$4,899
GILD SYK

GILD vs SYK: by the numbers

  • GILD is the larger company ($158.06B vs $119.06B market cap).
  • GILD trades at the lower earnings multiple (17.33 vs 35.95 P/E).
  • GILD converts more revenue to profit (30.99% vs 13.21% net margin).
  • SYK grew revenue faster over the past five years (11.42% vs 3.07% CAGR).
  • GILD pays the higher dividend yield (2.53% vs 1.11%).

Which is better, GILD or SYK?

Metric tally: GILD 13 · SYK 4

It depends on what you're optimizing for:

ValueGILD(lower P/E)
GrowthSYK(faster 5Y revenue CAGR)
IncomeGILD(higher dividend yield)
QualityGILD(higher ROIC)

Metrics side by side

Valuation

MetricGILDSYK
P/E ratio17.3335.95
Forward P/E13.1018.56
P/S ratio5.374.75
P/B ratio6.785.22
PEG ratio0.015.16
EV / EBITDA12.4221.49
FCF yield6.41%3.81%

Profitability

MetricGILDSYK
Gross margin79.35%63.67%
Operating margin38.26%21.34%
Net margin30.99%13.21%
ROE39.19%14.52%
ROIC21.53%8.53%

Dividends

MetricGILDSYK
Dividend yield2.53%1.11%
Payout ratio47.08%40.52%

Growth (annualized)

MetricGILDSYK
Revenue CAGR (5Y)3.07%11.42%
EPS CAGR (5Y)133.83%14.79%
FCF CAGR (5Y)3.30%11.01%
Total return CAGR (5Y)17.79%4.98%

Frequently asked

Which is better, GILD or SYK?
It depends on your goal. value: GILD (lower P/E); growth: SYK (faster 5Y revenue CAGR); income: GILD (higher dividend yield); quality: GILD (higher ROIC). Across all compared metrics, GILD leads 13 to 4.
Is GILD or SYK cheaper?
On trailing earnings, GILD is cheaper: GILD trades at a 17.33 P/E and SYK at 35.95.
Which has grown faster, GILD or SYK?
Over the past five years, SYK grew revenue faster — GILD at a 3.07% CAGR versus SYK at 11.42%.
Does GILD or SYK pay a bigger dividend?
GILD yields 2.53% and SYK yields 1.11% based on trailing dividends and the latest price.
Is GILD or SYK more profitable?
GILD runs the higher net margin — GILD at 30.99% versus SYK at 13.21%.
Which has been the better investment, GILD or SYK?
Over the past 10-year, SYK delivered the higher annualized total return — GILD at 8.16% versus SYK at 11.71%. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 17, 2026.