Gilead Sciences, Inc. (GILD) vs Stryker Corporation (SYK)
GILD leads on 13 of 17 compared metrics.
A side-by-side comparison of Gilead Sciences, Inc. and Stryker Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 17, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
Total return — GILD vs SYK
growth of $100 · last 30yGILD +16647.7%SYK +4798.7%GILD compounded faster
GILD SYK
GILD vs SYK: by the numbers
- •GILD is the larger company ($158.06B vs $119.06B market cap).
- •GILD trades at the lower earnings multiple (17.33 vs 35.95 P/E).
- •GILD converts more revenue to profit (30.99% vs 13.21% net margin).
- •SYK grew revenue faster over the past five years (11.42% vs 3.07% CAGR).
- •GILD pays the higher dividend yield (2.53% vs 1.11%).
Which is better, GILD or SYK?
Metric tally: GILD 13 · SYK 4It depends on what you're optimizing for:
ValueGILD(lower P/E)
GrowthSYK(faster 5Y revenue CAGR)
IncomeGILD(higher dividend yield)
QualityGILD(higher ROIC)
Metrics side by side
Valuation
| Metric | GILD | SYK |
|---|---|---|
| P/E ratio | 17.33● | 35.95 |
| Forward P/E | 13.10● | 18.56 |
| P/S ratio | 5.37 | 4.75● |
| P/B ratio | 6.78 | 5.22● |
| PEG ratio | 0.01● | 5.16 |
| EV / EBITDA | 12.42● | 21.49 |
| FCF yield | 6.41%● | 3.81% |
Profitability
| Metric | GILD | SYK |
|---|---|---|
| Gross margin | 79.35%● | 63.67% |
| Operating margin | 38.26%● | 21.34% |
| Net margin | 30.99%● | 13.21% |
| ROE | 39.19%● | 14.52% |
| ROIC | 21.53%● | 8.53% |
Dividends
| Metric | GILD | SYK |
|---|---|---|
| Dividend yield | 2.53%● | 1.11% |
| Payout ratio | 47.08% | 40.52% |
Growth (annualized)
| Metric | GILD | SYK |
|---|---|---|
| Revenue CAGR (5Y) | 3.07% | 11.42%● |
| EPS CAGR (5Y) | 133.83%● | 14.79% |
| FCF CAGR (5Y) | 3.30% | 11.01%● |
| Total return CAGR (5Y) | 17.79%● | 4.98% |
Frequently asked
- Which is better, GILD or SYK?
- It depends on your goal. value: GILD (lower P/E); growth: SYK (faster 5Y revenue CAGR); income: GILD (higher dividend yield); quality: GILD (higher ROIC). Across all compared metrics, GILD leads 13 to 4.
- Is GILD or SYK cheaper?
- On trailing earnings, GILD is cheaper: GILD trades at a 17.33 P/E and SYK at 35.95.
- Which has grown faster, GILD or SYK?
- Over the past five years, SYK grew revenue faster — GILD at a 3.07% CAGR versus SYK at 11.42%.
- Does GILD or SYK pay a bigger dividend?
- GILD yields 2.53% and SYK yields 1.11% based on trailing dividends and the latest price.
- Is GILD or SYK more profitable?
- GILD runs the higher net margin — GILD at 30.99% versus SYK at 13.21%.
- Which has been the better investment, GILD or SYK?
- Over the past 10-year, SYK delivered the higher annualized total return — GILD at 8.16% versus SYK at 11.71%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Gilead Sciences P/E ratioStryker P/E ratioGilead Sciences dividend yieldStryker dividend yieldGilead Sciences ROEStryker ROEGilead Sciences operating marginStryker operating marginGilead Sciences revenue growthStryker revenue growthGilead Sciences free cash flowStryker free cash flow
Gilead Sciences & Stryker appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 17, 2026.