Gilead Sciences, Inc. (GILD) vs Pfizer Inc. (PFE)

GILD leads on 10 of 15 compared metrics.

A side-by-side comparison of Gilead Sciences, Inc. and Pfizer Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Total return — GILD vs PFE

growth of $100 · last 30y
GILD +13408.8%PFE +128.5%GILD compounded faster
Log scale — wide-divergence pair
101001k10k100kStart $100200120062011201620212026$13,509$229
GILD PFE

GILD vs PFE: by the numbers

  • GILD is the larger company ($155.93B vs $149.38B market cap).
  • GILD trades at the lower earnings multiple (17.11 vs 20.01 P/E).
  • GILD converts more revenue to profit (30.99% vs 11.83% net margin).
  • PFE grew revenue faster over the past five years (8.22% vs 3.07% CAGR).
  • PFE pays the higher dividend yield (6.56% vs 1.91%).

Which is better, GILD or PFE?

Metric tally: GILD 10 · PFE 5

It depends on what you're optimizing for:

ValueGILD(lower P/E)
GrowthPFE(faster 5Y revenue CAGR)
IncomePFE(higher dividend yield)
QualityGILD(higher ROIC)

Valuation

MetricGILDPFE
P/E ratio17.1120.01
Forward P/E13.009.25
P/S ratio5.302.37
P/B ratio6.701.67
PEG ratio0.01
EV / EBITDA12.9112.72
FCF yield6.49%6.31%

Profitability

MetricGILDPFE
Gross margin79.35%69.35%
Operating margin38.26%23.45%
Net margin30.99%11.83%
ROE39.19%8.31%
ROIC21.53%8.84%

Dividends

MetricGILDPFE
Dividend yield1.91%6.56%
Payout ratio35.09%126.47%

Growth (annualized)

MetricGILDPFE
Revenue CAGR (5Y)3.07%8.22%
EPS CAGR (5Y)133.83%-3.78%
FCF CAGR (5Y)3.30%-3.79%
Total return CAGR (5Y)17.06%-3.33%

Frequently asked

Which is better, GILD or PFE?
It depends on your goal. value: GILD (lower P/E); growth: PFE (faster 5Y revenue CAGR); income: PFE (higher dividend yield); quality: GILD (higher ROIC). Across all compared metrics, GILD leads 10 to 5.
Is GILD or PFE cheaper?
On trailing earnings, GILD is cheaper: GILD trades at a 17.11 P/E and PFE at 20.01.
Which has grown faster, GILD or PFE?
Over the past five years, PFE grew revenue faster — GILD at a 3.07% CAGR versus PFE at 8.22%.
Does GILD or PFE pay a bigger dividend?
GILD yields 1.91% and PFE yields 6.56% based on trailing dividends and the latest price.
Is GILD or PFE more profitable?
GILD runs the higher net margin — GILD at 30.99% versus PFE at 11.83%.
Which has been the better investment, GILD or PFE?
Over the past 10-year, GILD delivered the higher annualized total return — GILD at 7.79% versus PFE at 2.13%. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.