Gilead Sciences, Inc. (GILD) vs Pfizer Inc. (PFE)

A side-by-side comparison of Gilead Sciences, Inc. and Pfizer Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 11, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnGILD vs PFE

growth of $100 · dividends reinvested · last 10y
GILD +164.6% (+10.2%/yr)PFE +37.3% (+3.2%/yr)GILD compounded faster over this window
100150200250Start $10020182020202220242026$265$137
GILD PFE

GILD vs PFE: by the numbers

  • GILD is the larger company ($178.44B vs $157.99B market cap).
  • PFE is profitable (6.81% net margin) while GILD runs a net loss (-10.64%).
  • PFE grew revenue faster over the past five years (6.29% vs 2.72% CAGR).
  • PFE pays the higher dividend yield (6.19% vs 2.22%).

Metrics side by side

Valuation

MetricGILDPFE
P/E ratioN/A36.63
Forward P/EN/A9.32
P/S ratio5.862.48
P/B ratio15.091.85
EV / EBITDAN/A10.15
FCF yield7.27%6.95%

Profitability

MetricGILDPFE
Gross margin79.59%71.32%
Operating margin39.74%25.08%
Net margin-10.64%6.81%
ROE-27.39%5.09%
ROIC-3.66%9.33%

Dividends

MetricGILDPFE
Dividend yield2.22%6.19%
Payout ratioN/A227.27%

Growth (annualized)

MetricGILDPFE
Revenue CAGR (5Y)2.72%6.29%
EPS CAGR (5Y)133.83%-3.78%
FCF CAGR (5Y)9.27%-3.11%
Total return CAGR (5Y)19.60%-4.68%

Frequently asked

Which has grown faster, GILD or PFE?
Over the past five years, PFE grew revenue faster — GILD at a 2.72% CAGR versus PFE at 6.29%.
Does GILD or PFE pay a bigger dividend?
GILD yields 2.22% and PFE yields 6.19% based on trailing dividends and the latest price.
Is GILD or PFE more profitable?
PFE runs the higher net margin — GILD at -10.64% versus PFE at 6.81%.
How have GILD and PFE total returns compared?
Over the past 10 years, GILD delivered 10.21% and PFE delivered 3.17% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 11, 2026.