Gilead Sciences, Inc. (GILD) vs Pfizer Inc. (PFE)
A side-by-side comparison of Gilead Sciences, Inc. and Pfizer Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 11, 2026. Differences are shown without an overall score or investment verdict.
GILD
Gilead Sciences, Inc.
$143.72HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT
PFE
Pfizer Inc.
$27.72HealthcareDelayed quote: Sep 11, 2026, 4:01 PM EDT
Total return — GILD vs PFE
growth of $100 · dividends reinvested · last 10yGILD +164.6% (+10.2%/yr)PFE +37.3% (+3.2%/yr)GILD compounded faster over this window
GILD PFE
GILD vs PFE: by the numbers
- •GILD is the larger company ($178.44B vs $157.99B market cap).
- •PFE is profitable (6.81% net margin) while GILD runs a net loss (-10.64%).
- •PFE grew revenue faster over the past five years (6.29% vs 2.72% CAGR).
- •PFE pays the higher dividend yield (6.19% vs 2.22%).
Metrics side by side
Valuation
| Metric | GILD | PFE |
|---|---|---|
| P/E ratio | N/A | 36.63 |
| Forward P/E | N/A | 9.32 |
| P/S ratio | 5.86 | 2.48 |
| P/B ratio | 15.09 | 1.85 |
| EV / EBITDA | N/A | 10.15 |
| FCF yield | 7.27% | 6.95% |
Profitability
| Metric | GILD | PFE |
|---|---|---|
| Gross margin | 79.59% | 71.32% |
| Operating margin | 39.74% | 25.08% |
| Net margin | -10.64% | 6.81% |
| ROE | -27.39% | 5.09% |
| ROIC | -3.66% | 9.33% |
Dividends
| Metric | GILD | PFE |
|---|---|---|
| Dividend yield | 2.22% | 6.19% |
| Payout ratio | N/A | 227.27% |
Growth (annualized)
| Metric | GILD | PFE |
|---|---|---|
| Revenue CAGR (5Y) | 2.72% | 6.29% |
| EPS CAGR (5Y) | 133.83% | -3.78% |
| FCF CAGR (5Y) | 9.27% | -3.11% |
| Total return CAGR (5Y) | 19.60% | -4.68% |
Frequently asked
- Which has grown faster, GILD or PFE?
- Over the past five years, PFE grew revenue faster — GILD at a 2.72% CAGR versus PFE at 6.29%.
- Does GILD or PFE pay a bigger dividend?
- GILD yields 2.22% and PFE yields 6.19% based on trailing dividends and the latest price.
- Is GILD or PFE more profitable?
- PFE runs the higher net margin — GILD at -10.64% versus PFE at 6.81%.
- How have GILD and PFE total returns compared?
- Over the past 10 years, GILD delivered 10.21% and PFE delivered 3.17% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Pfizer P/E ratioGilead Sciences dividend yieldPfizer dividend yieldGilead Sciences ROEPfizer ROEGilead Sciences operating marginPfizer operating marginGilead Sciences revenue growthPfizer revenue growthGilead Sciences free cash flowPfizer free cash flow
Gilead Sciences & Pfizer appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 11, 2026.