Gilead Sciences, Inc. (GILD) vs Merck & Co., Inc. (MRK)

GILD leads on 11 of 17 compared metrics.

A side-by-side comparison of Gilead Sciences, Inc. and Merck & Co., Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 15, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Compare

Total return — GILD vs MRK

growth of $100 · last 30y
GILD +16647.7%MRK +278.8%GILD compounded faster
Log scale — wide-divergence pair
101001k10k100kStart $100200120062011201620212026$16,748$379
GILD MRK

GILD vs MRK: by the numbers

  • MRK is the larger company ($283.78B vs $154.33B market cap).
  • GILD trades at the lower earnings multiple (16.93 vs 32.37 P/E).
  • GILD converts more revenue to profit (30.99% vs 13.62% net margin).
  • MRK grew revenue faster over the past five years (8.60% vs 3.07% CAGR).
  • MRK pays the higher dividend yield (3.63% vs 2.59%).

Which is better, GILD or MRK?

Metric tally: GILD 11 · MRK 6

It depends on what you're optimizing for:

ValueGILD(lower P/E)
GrowthMRK(faster 5Y revenue CAGR)
IncomeMRK(higher dividend yield)
QualityGILD(higher ROIC)

Metrics side by side

Valuation

MetricGILDMRK
P/E ratio16.9332.37
Forward P/E12.8111.92
P/S ratio5.244.33
P/B ratio6.636.19
PEG ratio0.011.81
EV / EBITDA12.7918.99
FCF yield6.56%4.97%

Profitability

MetricGILDMRK
Gross margin79.35%75.91%
Operating margin38.26%27.59%
Net margin30.99%13.62%
ROE39.19%19.48%
ROIC21.53%18.27%

Dividends

MetricGILDMRK
Dividend yield2.59%3.63%
Payout ratio47.08%57.12%

Growth (annualized)

MetricGILDMRK
Revenue CAGR (5Y)3.07%8.60%
EPS CAGR (5Y)133.83%21.21%
FCF CAGR (5Y)3.30%15.69%
Total return CAGR (5Y)16.97%12.14%

Frequently asked

Which is better, GILD or MRK?
It depends on your goal. value: GILD (lower P/E); growth: MRK (faster 5Y revenue CAGR); income: MRK (higher dividend yield); quality: GILD (higher ROIC). Across all compared metrics, GILD leads 11 to 6.
Is GILD or MRK cheaper?
On trailing earnings, GILD is cheaper: GILD trades at a 16.93 P/E and MRK at 32.37.
Which has grown faster, GILD or MRK?
Over the past five years, MRK grew revenue faster — GILD at a 3.07% CAGR versus MRK at 8.60%.
Does GILD or MRK pay a bigger dividend?
GILD yields 2.59% and MRK yields 3.63% based on trailing dividends and the latest price.
Is GILD or MRK more profitable?
GILD runs the higher net margin — GILD at 30.99% versus MRK at 13.62%.
Which has been the better investment, GILD or MRK?
Over the past 10-year, MRK delivered the higher annualized total return — GILD at 7.87% versus MRK at 11.31%. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 15, 2026.