Gilead Sciences, Inc. (GILD) vs Merck & Co., Inc. (MRK)

A side-by-side comparison of Gilead Sciences, Inc. and Merck & Co., Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 31, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnGILD vs MRK

growth of $100 · dividends reinvested · last 30y
GILD +32553.7%MRK +1009.8%GILD compounded faster
Log scale — wide-divergence pair
101001k10k100kStart $100200120062011201620212026$32,654$1,110
GILD MRK

GILD vs MRK: by the numbers

  • MRK is the larger company ($320.56B vs $162.99B market cap).
  • GILD trades at the lower trailing earnings multiple (17.89 vs 36.56 P/E), one valuation lens rather than an overall verdict.
  • GILD converts more revenue to profit (30.99% vs 13.62% net margin).
  • MRK grew revenue faster over the past five years (8.60% vs 3.07% CAGR).
  • MRK pays the higher dividend yield (2.59% vs 2.45%).

Metrics side by side

Valuation

MetricGILDMRK
P/E ratio17.8936.56
Forward P/EN/A46.80
P/S ratio5.544.89
P/B ratio7.006.99
PEG ratio0.011.81
EV / EBITDA12.6815.06
FCF yield6.22%4.40%

Profitability

MetricGILDMRK
Gross margin79.35%75.91%
Operating margin38.26%36.17%
Net margin30.99%13.62%
ROE39.19%19.48%
ROIC21.53%18.27%

Dividends

MetricGILDMRK
Dividend yield2.45%2.59%
Payout ratio47.08%46.03%

Growth (annualized)

MetricGILDMRK
Revenue CAGR (5Y)3.07%8.60%
EPS CAGR (5Y)133.83%21.21%
FCF CAGR (5Y)3.30%15.69%
Total return CAGR (5Y)18.19%14.56%

Frequently asked

Which has the lower trailing P/E, GILD or MRK?
GILD has the lower trailing P/E: GILD trades at 17.89 and MRK at 36.56. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, GILD or MRK?
Over the past five years, MRK grew revenue faster — GILD at a 3.07% CAGR versus MRK at 8.60%.
Does GILD or MRK pay a bigger dividend?
GILD yields 2.45% and MRK yields 2.59% based on trailing dividends and the latest price.
Is GILD or MRK more profitable?
GILD runs the higher net margin — GILD at 30.99% versus MRK at 13.62%.
How have GILD and MRK total returns compared?
Over the past 10 years, GILD delivered 8.94% and MRK delivered 12.17% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 31, 2026.