Gilead Sciences, Inc. (GILD) vs Intuitive Surgical, Inc. (ISRG)
A side-by-side comparison of Gilead Sciences, Inc. and Intuitive Surgical, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 29, 2026. Differences are shown without an overall score or investment verdict.
GILD
Gilead Sciences, Inc.
$133.27HealthcareDelayed quote: Jul 29, 2026, 3:35 PM EDT
ISRG
Intuitive Surgical, Inc.
$352.71HealthcareDelayed quote: Jul 29, 2026, 3:34 PM EDT
Total return — GILD vs ISRG
growth of $100 · dividends reinvested · last 26yGILD +9311.6%ISRG +17722.7%ISRG compounded faster
GILD ISRG
GILD vs ISRG: by the numbers
- •GILD is the larger company ($165.46B vs $124.60B market cap).
- •GILD trades at the lower trailing earnings multiple (18.30 vs 41.16 P/E), one valuation lens rather than an overall verdict.
- •GILD converts more revenue to profit (30.99% vs 28.45% net margin).
- •ISRG grew revenue faster over the past five years (16.41% vs 3.07% CAGR).
- •GILD pays a dividend (2.40% yield), while ISRG has no payments in the available dividend history.
Metrics side by side
Valuation
| Metric | GILD | ISRG |
|---|---|---|
| P/E ratio | 18.30 | 41.16 |
| Forward P/E | N/A | 33.60 |
| P/S ratio | 5.66 | 11.75 |
| P/B ratio | 7.16 | 7.14 |
| PEG ratio | 0.01 | 3.17 |
| EV / EBITDA | 12.95 | 30.00 |
| FCF yield | 6.07% | 2.48% |
Profitability
| Metric | GILD | ISRG |
|---|---|---|
| Gross margin | 79.35% | 66.68% |
| Operating margin | 38.26% | 31.28% |
| Net margin | 30.99% | 28.45% |
| ROE | 39.19% | 17.28% |
| ROIC | 21.53% | 13.71% |
Dividends
| Metric | GILD | ISRG |
|---|---|---|
| Dividend yield | 2.40% | N/A |
| Payout ratio | 47.08% | N/A |
Growth (annualized)
| Metric | GILD | ISRG |
|---|---|---|
| Revenue CAGR (5Y) | 3.07% | 16.41% |
| EPS CAGR (5Y) | 133.83% | 21.51% |
| FCF CAGR (5Y) | 3.30% | 14.17% |
| Total return CAGR (5Y) | 18.12% | 2.22% |
Frequently asked
- Which has the lower trailing P/E, GILD or ISRG?
- GILD has the lower trailing P/E: GILD trades at 18.30 and ISRG at 41.16. P/E is one valuation measure and does not by itself establish which business is cheaper.
- Which has grown faster, GILD or ISRG?
- Over the past five years, ISRG grew revenue faster — GILD at a 3.07% CAGR versus ISRG at 16.41%.
- Does GILD or ISRG pay a bigger dividend?
- GILD pays a dividend (2.40% yield), while ISRG has no payments in the available dividend history.
- Is GILD or ISRG more profitable?
- GILD runs the higher net margin — GILD at 30.99% versus ISRG at 28.45%.
- How have GILD and ISRG total returns compared?
- Over the past 10 years, GILD delivered 8.95% and ISRG delivered 16.79% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Gilead Sciences P/E ratioIntuitive Surgical P/E ratioGilead Sciences dividend yieldIntuitive Surgical dividend yieldGilead Sciences ROEIntuitive Surgical ROEGilead Sciences operating marginIntuitive Surgical operating marginGilead Sciences revenue growthIntuitive Surgical revenue growthGilead Sciences free cash flowIntuitive Surgical free cash flow
Gilead Sciences & Intuitive Surgical appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 29, 2026.