Gilead Sciences, Inc. (GILD) vs Intuitive Surgical, Inc. (ISRG)

A side-by-side comparison of Gilead Sciences, Inc. and Intuitive Surgical, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 11, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnGILD vs ISRG

growth of $100 · dividends reinvested · last 10y
GILD +161.3% (+10.1%/yr)ISRG +372.7% (+16.8%/yr)ISRG compounded faster over this window
200400600800Start $10020182020202220242026$261$473
GILD ISRG

GILD vs ISRG: by the numbers

  • GILD is the larger company ($178.44B vs $130.41B market cap).
  • ISRG is profitable (28.45% net margin) while GILD runs a net loss (-10.64%).
  • ISRG grew revenue faster over the past five years (16.41% vs 2.72% CAGR).
  • GILD pays a dividend (2.22% yield), while ISRG has no payments in the available dividend history.

Metrics side by side

Valuation

MetricGILDISRG
P/E ratioN/A42.00
Forward P/EN/A34.18
P/S ratio5.8611.82
P/B ratio15.097.18
EV / EBITDAN/A30.16
FCF yield7.27%2.47%

Profitability

MetricGILDISRG
Gross margin79.59%66.68%
Operating margin39.74%31.28%
Net margin-10.64%28.45%
ROE-27.39%17.28%
ROIC-3.66%15.11%

Dividends

MetricGILDISRG
Dividend yield2.22%N/A

Growth (annualized)

MetricGILDISRG
Revenue CAGR (5Y)2.72%16.41%
EPS CAGR (5Y)133.83%21.51%
FCF CAGR (5Y)9.27%14.17%
Total return CAGR (5Y)19.60%1.11%

Frequently asked

Which has grown faster, GILD or ISRG?
Over the past five years, ISRG grew revenue faster — GILD at a 2.72% CAGR versus ISRG at 16.41%.
Does GILD or ISRG pay a bigger dividend?
GILD pays a dividend (2.22% yield), while ISRG has no payments in the available dividend history.
Is GILD or ISRG more profitable?
ISRG runs the higher net margin — GILD at -10.64% versus ISRG at 28.45%.
How have GILD and ISRG total returns compared?
Over the past 10 years, GILD delivered 10.21% and ISRG delivered 16.97% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 11, 2026.