Gilead Sciences, Inc. (GILD) vs Intuitive Surgical, Inc. (ISRG)
A side-by-side comparison of Gilead Sciences, Inc. and Intuitive Surgical, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 11, 2026. Differences are shown without an overall score or investment verdict.
GILD
Gilead Sciences, Inc.
$143.72HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT
ISRG
Intuitive Surgical, Inc.
$369.15HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT
Total return — GILD vs ISRG
growth of $100 · dividends reinvested · last 10yGILD +161.3% (+10.1%/yr)ISRG +372.7% (+16.8%/yr)ISRG compounded faster over this window
GILD ISRG
GILD vs ISRG: by the numbers
- •GILD is the larger company ($178.44B vs $130.41B market cap).
- •ISRG is profitable (28.45% net margin) while GILD runs a net loss (-10.64%).
- •ISRG grew revenue faster over the past five years (16.41% vs 2.72% CAGR).
- •GILD pays a dividend (2.22% yield), while ISRG has no payments in the available dividend history.
Metrics side by side
Valuation
| Metric | GILD | ISRG |
|---|---|---|
| P/E ratio | N/A | 42.00 |
| Forward P/E | N/A | 34.18 |
| P/S ratio | 5.86 | 11.82 |
| P/B ratio | 15.09 | 7.18 |
| EV / EBITDA | N/A | 30.16 |
| FCF yield | 7.27% | 2.47% |
Profitability
| Metric | GILD | ISRG |
|---|---|---|
| Gross margin | 79.59% | 66.68% |
| Operating margin | 39.74% | 31.28% |
| Net margin | -10.64% | 28.45% |
| ROE | -27.39% | 17.28% |
| ROIC | -3.66% | 15.11% |
Dividends
| Metric | GILD | ISRG |
|---|---|---|
| Dividend yield | 2.22% | N/A |
Growth (annualized)
| Metric | GILD | ISRG |
|---|---|---|
| Revenue CAGR (5Y) | 2.72% | 16.41% |
| EPS CAGR (5Y) | 133.83% | 21.51% |
| FCF CAGR (5Y) | 9.27% | 14.17% |
| Total return CAGR (5Y) | 19.60% | 1.11% |
Frequently asked
- Which has grown faster, GILD or ISRG?
- Over the past five years, ISRG grew revenue faster — GILD at a 2.72% CAGR versus ISRG at 16.41%.
- Does GILD or ISRG pay a bigger dividend?
- GILD pays a dividend (2.22% yield), while ISRG has no payments in the available dividend history.
- Is GILD or ISRG more profitable?
- ISRG runs the higher net margin — GILD at -10.64% versus ISRG at 28.45%.
- How have GILD and ISRG total returns compared?
- Over the past 10 years, GILD delivered 10.21% and ISRG delivered 16.97% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Intuitive Surgical P/E ratioGilead Sciences dividend yieldGilead Sciences ROEIntuitive Surgical ROEGilead Sciences operating marginIntuitive Surgical operating marginGilead Sciences revenue growthIntuitive Surgical revenue growthGilead Sciences free cash flowIntuitive Surgical free cash flow
Gilead Sciences & Intuitive Surgical appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 11, 2026.