GH Research PLC (GHRS) vs Stoke Therapeutics, Inc. (STOK)

A side-by-side comparison of GH Research PLC and Stoke Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — GHRS vs STOK

growth of $100 · dividends reinvested · last 5y
GHRS +15.2% (+2.9%/yr)STOK -29.9% (-6.9%/yr)GHRS compounded faster over this window
050100150Start $10020222023202420252026$115$70
GHRS STOK

GHRS vs STOK: by the numbers

  • •STOK is the larger company ($1.57B vs $1.48B market cap).
  • •Both run net losses; GHRS's is the smaller (0.00% vs -753.60% net margin).

Metrics side by side

Valuation

MetricGHRSSTOK
P/S ratioN/A57.00
P/B ratio4.104.55

Profitability

MetricGHRSSTOK
Gross margin0.00%100.00%
Operating margin0.00%-11.16%
Net margin0.00%-753.60%
ROE-17.32%-60.17%
ROIC-19.87%-63.12%

Growth (annualized)

MetricGHRSSTOK
Total return CAGR (5Y)0.52%-0.24%

Frequently asked

How have GHRS and STOK total returns compared?
Over the past 5 years, GHRS delivered 0.52% and STOK delivered -0.24% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.