Geron Corporation (GERN) vs Gyre Therapeutics, Inc. (GYRE)
A side-by-side comparison of Geron Corporation and Gyre Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
GERN
Geron Corporation
$1.21HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
GYRE
Gyre Therapeutics, Inc.
$7.35HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
Total return — GERN vs GYRE
growth of $100 · dividends reinvested · last 10yGERN -46.7% (-6.1%/yr)GYRE -79.5% (-14.6%/yr)GERN compounded faster over this window
GERN GYRE
GERN vs GYRE: by the numbers
- •GYRE is the larger company ($819M vs $776M market cap).
- •Both run net losses; GYRE's is the smaller (-14.52% vs -34.17% net margin).
- •GERN grew revenue faster over the past five years (247.85% vs 84.92% CAGR).
Metrics side by side
Valuation
| Metric | GERN | GYRE |
|---|---|---|
| P/S ratio | 3.79 | 6.86 |
| P/B ratio | 3.55 | 7.59 |
Profitability
| Metric | GERN | GYRE |
|---|---|---|
| Gross margin | 97.42% | 94.30% |
| Operating margin | -29.28% | 9.86% |
| Net margin | -34.17% | -14.52% |
| ROE | -31.97% | -13.30% |
| ROIC | -8.34% | -9.77% |
Growth (annualized)
| Metric | GERN | GYRE |
|---|---|---|
| Revenue CAGR (5Y) | 247.85% | 84.92% |
| Total return CAGR (5Y) | -1.87% | -0.34% |
Frequently asked
- Which has grown faster, GERN or GYRE?
- Over the past five years, GERN grew revenue faster — GERN at a 247.85% CAGR versus GYRE at 84.92%.
- How have GERN and GYRE total returns compared?
- Over the past 10 years, GERN delivered -6.18% and GYRE delivered -14.92% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Geron ROEGyre Therapeutics ROEGeron operating marginGyre Therapeutics operating marginGeron revenue growthGyre Therapeutics revenue growthGeron free cash flowGyre Therapeutics free cash flow
Geron & Gyre Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.